Korilog announces the integration of KoriBlast within Genostar's Metabolic Pathway Builder bioinformatics platform. Korilog's databank exploration software extends Metabolic Pathway Builder, enabling users to conduct large scale sequence studies bringing into play genomic, proteomic, transcriptomic and pathway data.

Metabolic Pathway Builder seamlessly integrates a suite of analytical methods and data for genomic, proteic and metabolic research, enabling users to perform comparative genomics, predict protein functions and enzymatic activity, and both explore and visualize metabolic pathways on multiple organisms of interest.

Koriblast is an easy to use, graphically-driven software module for global exploration of biological sequence databanks. It offers a unified access to remote and local sequence and data repositories. Users can take advantage of the multifunctional, configurable interface to design powerful search strategies combining batch sequence comparisons and to efficiently retrieve and filter their data. KoriBlast also features a set of comprehensive viewers to analyze search results, from sequences to 3D structures.

By integrating the software platforms, this partnership brings researchers a world-class, user friendly solution for analysis of NGS-generated sequences and expression data from genome to metabolome. Benefits include the ability to:

• Efficiently and accurately annotate or reannotate genomic and proteic sequences, Map sequences on pathways
• Identify and analyze syntenies and the metabolic reactions catalyzed by their gene products
• Rapidly read, assemble and analyze data in all common formats, whether from complete chromosomes or large sets of newly sequenced cDNAs or contigs
• Prepare and use personal sequence data repositories

The integrated platform enables a wide range of applications for public research institutes and agri-business, biotechnology and pharmaceutical industries:

• Vaccine discovery and development
• Animal health & nutrition
• Diagnostics
• Agro-foods
• Cosmetics research
• Infectious diseases

About Genostar - www.genostar.com

Genostar is a bioinformatics company specializing in solutions for biological data analysis from genome to metabolome. Our software, data and expert services allow scientists to efficiently and visually interpret their sequence, expression and metabolic data, accelerating time-to-discovery. Genostar's strength in annotation and comparative analysis of multiple organisms contributes to infectious disease research, vaccine discovery, diagnostics and optimization of probiotics. Our integrated, flexible platform brings together a wide range of methods and data modeling, streamlining workflow, and making reporting and sharing of results fast and easy.

Contact: , COO. +33 476 971 070.

About Korilog - www.korilog.com

Korilog is a bioinformatics company providing academic and industry research laboratories with next generation software solutions in the key areas of data integration, exploration, management and visualization. Korilog provides ready-to-use graphical software (koriblast.com, koriviewer.com) enabling comprehensive exploration of sequence databanks and associated data. The company provides as well expert services to integrate specialized modules in Korilog' software, or create tailored tools and databanks to support researchers in their R&D activities.

Contact: , CEO. +33 960 368 038.

KoriBlast 2.7

In this new release, the following features have been added:

1. Query NCBI major databanks and get sequences of interest using the Document Viewer's NCBI Entrez DataBase Explorer Tool. Sequence retrieval can be done interactively or in batch mode.
2. Export data in plain text files. Text format includes extended hit table and/or pairwise sequence alignments.
3. View protein sequences using the Hydrophobic Cluster Analysis (HCA) drawing system
4. Benefit from an extended display of summaries in the Search Module.
5. When creating local Blast databanks, KoriBlast now gets Fasta sequences out of these banks, instead of querying the NCBI.
6. For proteomics studies, KoriBlast computes theoretical pI and molecular weight.

Read more in the complete release note

KoriViewer is a lightweight edition of KoriBlast providing the researchers with a full-featured graphical solution to analyse the results of in-house made Blast results.

From the researchers point of view, they will benefit from the complete Analyse module of KoriBlast.

From the IT administrators point of view, we are glad to provide them with a client-server based installation, enabling the deployment of KoriViewer within existing Blast search servers.

Read more.

In this new release, the following features have been added:

1. PSI-Blast searches are available from the Search Module and the Analyse Module has been adapted to enable extended analysis of the results (see figure below, and view this video)
2. Prepare personal Blast databanks from native GenBank, Genpept, EMBL, SwissProt and Uniprot files, using either plain text or gzipped compressed files (view this video)
3. Install pre-formatted NCBI Blast databanks directly from their native 'tar.gz' files (view this video)
4. Design search filters enabling pattern matching on hit sequences
5. Compare search results to find new, common or deleted hits
6. Export KoriBlast data files and filters to share with colleagues having KoriBlast or BlastViewer
7. New Sequence Viewer to display and manipulate sequences (extract, translate, get compositions) downloaded from public repositories (see figure below)
8. Better handling of large projects involving thousands of sequences

Read more in the complete release note

In this new release, two major tools have been added: a Project Manager and a Distance Tree viewer. The former enables the user to organize his/her search jobs using multi-level hierarchies. The latter provide the user with an integrated viewer aims at exploring distance trees created from query-anchored sequence alignments.

  Other new features include:

1. A new and more compact display of query-anchored alignments, including a Sequence Logo Viewer (Analyse Module)
2. New export formats for images, alignments and trees. Creation of PDF reports (Search and Analyse Modules).
3. The capability of analysing search results procuded by ScanPS (Analyse Module)

Read more