Elongation factor P is required for EII Glc translation in Corynebacterium glutamicum due to an essential polyproline motif

Elongation factor P is required for EII Glc translation in Corynebacterium glutamicum due to an essential polyproline motif

Translating ribosomes require elongation issue P (EF-P) to include consecutive prolines (XPPX) into nascent peptide chains. The proteome of Corynebacterium glutamicum ATCC 13032 accommodates a complete of 1,468 XPPX motifs, a lot of that are present in proteins concerned in main and secondary metabolism. We present right here that synthesis of EIIGlcĀ , the glucose-specific permease […]