Rv3634c from Mycobacterium tuberculosis H37Rv encodes an enzyme with UDP-Gal/Glc and UDP-GalNAc 4-epimerase activities.

Rv3634c from Mycobacterium tuberculosis H37Rv encodes an enzyme with UDP-Gal/Glc and UDP-GalNAc 4-epimerase activities.

A bioinformatics research revealed that Mycobacterium tuberculosis H37Rv (Mtb) incorporates sequence homologs of Campylobacter jejuni protein glycosylation enzymes. The ORF Rv3634c from Mtb was recognized as a sequence homolog of C. jejuni UDP-Gal/GalNAc 4-epimerase. This research reviews the cloning of Rv3634c and its expression as an N-terminal His-tagged protein. The recombinant protein was proven to […]