An Exploratory Pilot Study of Genetic Marker for IgE-Mediated Allergic Diseases with Expressions of FcεR1α and Cε.

An Exploratory Pilot Study of Genetic Marker for IgE-Mediated Allergic Diseases with Expressions of FcεR1α and Cε.

The excessive affinity immunoglobulin E (IgE) receptor-FcεR1 is principally expressed on the floor of effector cells. Cross-linking of IgE Abs sure to FcεR1 by multi-valent antigens can induce the activation of those cells and the secretion of inflammatory mediators. Since FcεR1 performs a central function within the induction and upkeep of allergic responses, this research […]