The glycan role in the glycopeptide immunogenicity revealed by atomistic simulations and spectroscopic experiments on the multiple sclerosis biomarker CSF114(Glc).

The glycan role in the glycopeptide immunogenicity revealed by atomistic simulations and spectroscopic experiments on the multiple sclerosis biomarker CSF114(Glc).

Glycoproteins are sometimes acknowledged as not-self molecules by antibodies triggering the onset of extreme autoimmune illnesses resembling A number of Sclerosis (MS). Thus, the event of antigen-mimicking biomarkers represents a sexy technique for an early analysis of the illness. An instance is the artificial glycopeptide CSF114(Glc), which was designed and examined as MS biomarker and […]