Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity

Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity

Serological assays have been extensively employed in the course of the coronavirus illness 2019 (COVID-19) pandemic to measure¬†antibody¬†responses to extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to trace seroconversion in populations. Nevertheless, at the moment accessible assays don’t enable dedication of neutralization capability throughout the assay protocol. Moreover, business serology assays have a excessive¬†purchase-in […]

Dexamethasone transiently enhances transgene expression in the liver when administered at late phase post long term AAV transduction

Dexamethasone transiently enhances transgene expression in the liver when administered at late phase post long term AAV transduction

Glucocorticoids have anti-inflammatory and immunosuppressive features and have generally been used for stopping liver toxicity after the systemic software of a excessive dose of adeno-associated virus (AAV) vector for gene remedy. Medical research have reported that glucocorticoids have rescued Issue IX (FIX) expression in hemophilia B sufferers who confirmed a lowered FIX expression at 6 […]