Serological assays have been extensively employed in the course of the coronavirus illness 2019 (COVID-19) pandemic to measure antibody responses to extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to trace seroconversion in populations. Nevertheless, at the moment accessible assays don’t enable dedication of neutralization capability throughout the assay protocol. Moreover, business serology assays have a excessive purchase-in […]
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Dexamethasone transiently enhances transgene expression in the liver when administered at late phase post long term AAV transduction
Glucocorticoids have anti-inflammatory and immunosuppressive features and have generally been used for stopping liver toxicity after the systemic software of a excessive dose of adeno-associated virus (AAV) vector for gene remedy. Medical research have reported that glucocorticoids have rescued Issue IX (FIX) expression in hemophilia B sufferers who confirmed a lowered FIX expression at 6 […]