Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor

Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor

Imaging strategies primarily based on fluorescence and bioluminescence have been necessary instruments in visualizing tumor development and finding out the impact of medication and immunotherapies on tumor immune microenvironment in animal fashions of most cancers. Nonetheless, transgenic expression of overseas proteins could induce immune responses in immunocompetent syngeneic tumor transplant fashions and increase the efficacy […]