Elongation factor P is required for EII Glc translation in Corynebacterium glutamicum due to an essential polyproline motif

Elongation factor P is required for EII Glc translation in Corynebacterium glutamicum due to an essential polyproline motif

Translating ribosomes require elongation issue P (EF-P) to include consecutive prolines (XPPX) into nascent peptide chains. The proteome of Corynebacterium glutamicum ATCC 13032 accommodates a complete of 1,468 XPPX motifs, a lot of that are present in proteins concerned in main and secondary metabolism. We present right here that synthesis of EIIGlc , the glucose-specific permease of the phosphoenolpyruvate (PEP): sugar phosphotransferase system (PTS) encoded by ptsG, is strongly depending on EF-P, as an efp deletion mutant grows poorly on glucose as sole carbon supply.

The quantity of EIIGlc is strongly lowered on this mutant, which consequently ends in a decrease charge of glucose uptake. Strikingly, the XPPX motif is crucial for the exercise of EIIGlc , and substitution of the prolines results in inactivation of the protein. Lastly, translation of GntR2, a transcriptional activator of ptsG, can also be depending on EF-P. Nonetheless, its lowered quantity within the efp mutant may be compensated for by different regulators. These outcomes reveal for the primary time a translational bottleneck involving manufacturing of the key glucose transporter EIIGlc , which has implications for future pressure engineering methods.

ZmMPK6 and ethylene signaling negatively regulate the buildup of anti-insect metabolites DIMBOA and DIMBOA-Glc in maize inbred line A188

2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and DIMBOA-glucoside (DIMBOA-Glc) are anti-insect benzoxazinoids in maize. But little or no is understood about how they’re regulated. Reverse genetics, kinase exercise evaluation, phytohormone and DIMBOA/DIMBOA-Glc quantification, bioassays, and transcriptome evaluation had been employed to review the perform of ZmMPK6, a mitogen-activated protein kinase, in maize response to herbivory. ZmMPK6 was quickly activated by wounding and simulated herbivory.

Ethylene complementation experiment revealed that ZmMPK6 repressed the buildup of DIMBOA/DIMBOA-Glc in an ethylene-dependent method. Transcriptome evaluation revealed that ZmMPK6 may meditate the transcription of BX1 by controlling a MYB transcription issue that’s doubtless positioned within the ethylene signaling pathway, and moreover, ZmMPK6 and ethylene signaling additionally particularly and generally regulate the transcription of different benzoxazinoid biosynthetic genes.

We additionally present that completely different maize strains have very completely different responses to simulated herbivory when it comes to ZmMPK6 activation, ethylene emission, and benzoxazinoid ranges. These outcomes uncover that ZmMPK6 and ethylene pathway are novel repressors of DIMBOA/DIMBOA-Glc and supply new perception into the regulatory mechanisms underlying these two pathways. Silencing ZmMPK6 in maize A188 compromised simulated herbivory-induced ethylene ranges however not these of jasmonic acid or salicylic acid, and the ZmMPK6-silenced vegetation exhibited elevated DIMBOA/DIMBOA-Glc and bug resistance.

Elongation factor P is required for EII Glc translation in Corynebacterium glutamicum due to an essential polyproline motif

Evaluation of the Rest-Enhancing Properties of a Nitroxide-Based mostly Distinction Agent TEEPO-Glc with In Vivo Magnetic Resonance Imaging.

Magnetic resonance imaging examinations are continuously carried out utilizing distinction brokers to enhance the picture high quality. Virtually all clinically used distinction brokers are primarily based on paramagnetic metals and lack in selectivity and specificity. A bunch of secure natural radicals, nitroxides, has raised curiosity as new metal-free distinction brokers for MRI. Their buildings can simply be modified to include completely different functionalities.

Within the current examine, a secure nitroxide TEEPO was linked to a glucose moiety (Glc) to assemble a water-soluble, doubtlessly tumor-targeting compound with contrast-enhancing capability. The power was assessed with in vivo MRI experiments. The constructed TEEPO-Glc agent proved to shorten the T1 rest time in tumor, whereas the T1 time in wholesome mind tissue remained the identical. The outcomes point out the potential of TEEPO-Glc as a useful addition to the rising area of metal-free distinction enhancement in MRI-based diagnostics.

SPION-Embellished Exosome Delivered BAY55-9837 Focusing on the Pancreas by means of Magnetism to Enhance the Blood GLC Response.

BAY55-9837, a possible therapeutic peptide within the remedy of kind 2 diabetes mellitus (T2DM), is able to inducing glucose (GLC)-dependent insulin secretion. Nonetheless, the therapeutic good thing about BAY55-9837 is restricted by its brief half-life, lack of focusing on capability, and poor blood GLC response. How you can enhance the blood GLC response of BAY55-9837 is an present drawback that must be solved. On this examine, a way for getting ready BAY55-9837-loaded exosomes coupled with superparamagnetic iron oxide nanoparticle (SPIONs) with pancreas islet focusing on exercise and an enhanced blood GLC response with the assistance of an exterior magnetic power (MF) is demonstrated.

The plasma half-life of BAY55-9837 loaded in exosome-SPION is 27-fold longer than that of BAY55-9837. The energetic focusing on property of SIPONs allows BAY-exosomes to achieve a positive focusing on property, which improves the BAY55-9837 blood GLC response capability with the assistance of an exterior MF. In vivo research present that BAY-loaded exosome-based car supply enhances pancreas islet focusing on beneath an exterior MF and markedly will increase insulin secretion, thereby resulting in the alleviation of hyperglycemia. The continual administration of BAY-exosome-SPION/MF considerably improves glycosylated hemoglobin and lipid profiles. BAY-exosome-SPION/MF perhaps a promising candidate for a peptide drug service for T2DM with a greater blood GLC response.

The consequences and mechanisms of a biosynthetic ginsenoside 3β,12β-Di-O-Glc-PPD on non-small cell lung most cancers.

A biosynthetic ginsenoside, 3-O-β-D-glucopyranosyl-12-O-β-D-glucopyranosyl-dammar-24-ene-3β, 12β, 20S-triol (C3C12PPD), confirmed antitumor exercise towards many tumor cells in vitro, particularly had higher anti-lung most cancers exercise than Rg3 in vitro and in vivo.

FITC anti-human CD226 (DNAM-1)

E16FHF226-025 25 tests
EUR 368.33
Description: Available in various conjugation types.

FITC anti-human CD226 (DNAM-1)

E16FHF226-100 100 tests
EUR 845
Description: Available in various conjugation types.

Purified anti-human CD226 (DNAM-1)

E16FHU226-100U 100 μg
EUR 455
Description: Available in various conjugation types.

Anti-Human CD226/DNAM-1 Antibody (SAA0074)

MBS1564467-01mg 0.1mg
EUR 405

Anti-Human CD226/DNAM-1 Antibody (SAA0074)

MBS1564467-5x01mg 5x0.1mg
EUR 1520

Mouse Monoclonal anti-human DNAM-1 (CD226)

hAP-0248 100ug
EUR 250

Sheep Polyclonal anti-Human DNAM-1 (CD226)

hAP-5851 50ug
EUR 400

Recombinant Human DNAM-1/CD226 Protein

RP00324 10μg
EUR 123.99

Recombinant Human DNAM-1/CD226 Protein

RP00958 10μg
EUR 123.99

Recombinant Human DNAM-1/CD226 Protein

RP02028 100μg
EUR 233.81

Recombinant Human DNAM-1/CD226 Protein

RP02251 10μg
EUR 209.01

PE anti-mouse CD226 (DNAM-1)

E16FMP226-025U 25 μg
EUR 433.33
Description: Available in various conjugation types.

PE anti-mouse CD226 (DNAM-1)

E16FMP226-100U 100 μg
EUR 1148.33
Description: Available in various conjugation types.

DNAM-1 Antibody

B0843-100ul 100μl
EUR 217
Description: DNAM-1 Rabbit Polyclonal Antibody

DNAM-1 Antibody

B0843-50ul 50μl
EUR 143.5
Description: DNAM-1 Rabbit Polyclonal Antibody

DNAM-1 Antibody

C30497-100ul 100μl
EUR 217
Description: DNAM-1 Rabbit Polyclonal Antibody

DNAM-1 Antibody

C30497-50ul 50μl
EUR 143.5
Description: DNAM-1 Rabbit Polyclonal Antibody

APC anti-mouse CD226 (DNAM-1)

E16FMA226-025U 25 μg
EUR 498.33
Description: Available in various conjugation types.

APC anti-mouse CD226 (DNAM-1)

E16FMA226-100U 100 μg
EUR 1256.67
Description: Available in various conjugation types.

FITC anti-mouse CD226 (DNAM-1)

E16FMF226-050U 50 μg
EUR 541.67
Description: Available in various conjugation types.

Human DNAM-1 / CD226 Protein, Fc Tag

DN1-H5257 1mg
EUR 267.5
Description: Human DNAM-1, Fc Tag (DN1-H5257) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557).

PE Rabbit anti-Human DNAM-1/CD226 mAb

A23591 25μg
EUR 1557.4
Description: Recombinant fusion protein containing a sequence corresponding to amino acids 250-473 of human MEF2A+MEF2C (Q06413).

Human DNAM-1 / CD226 Protein, His Tag

DN1-H52H6 1mg
EUR 267.5
Description: Human DNAM-1, His Tag (DN1-H52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557).

Human DNAM-1 Protein, mFc-His Tag

E33P100050 10 μg
EUR 225

Human DNAM-1 Protein, mFc-His Tag

MBS8575099-001mg 0.01mg
EUR 305

Human DNAM-1 Protein, mFc-His Tag

MBS8575099-5x001mg 5x0.01mg
EUR 1220

Mouse Monoclonal anti-Human CD226 (DNAM-1) Antibody

xAP-0182 100ug
EUR 280

Mouse Monoclonal anti-Human CD226 (DNAM-1) Antibody

xAP-0183 100ug
EUR 280

Active Recombinant Human DNAM-1/CD226 Protein

RP00283 10 μg
EUR 78

OKRC00369-96W - DNAM-1 ELISA Kit (Human)

OKRC00369-96W 96Wells
EUR 525

Human DNAM-1/CD226 ELISA Kit PicoKine®

EK2161 96 wells/kit, with removable strips.
EUR 499
Description: Human DNAM-1/CD226 ELISA Kit PicoKine® (96 Tests). Quantitate Human CD226 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 5 pg/ml.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

AP76445 1mg
EUR 1879

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-10ug 10ug
EUR 151.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-1mg 1mg
EUR 1581.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-500ug 500ug
EUR 1155.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-50ug 50ug
EUR 333.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

NE Purified anti-mouse CD226 (DNAM-1)

E16FMY226-500U 500 μg
EUR 1625
Description: Available in various conjugation types.

Rabbit anti Mouse DNAM-1  Monoclonal Antibody

MBS2544521-006mL 0.06mL
EUR 335

Rabbit anti Mouse DNAM-1  Monoclonal Antibody

MBS2544521-012mL 0.12mL
EUR 520

Rabbit anti Mouse DNAM-1  Monoclonal Antibody

MBS2544521-02mL 0.2mL
EUR 800

CD226 / DNAM-1 Antibody

20-abx119383
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

CD226/DNAM-1 Antibody

E11-184778 100ug/100ul
EUR 225
Description: Available in various conjugation types.

CD226/DNAM-1 Antibody

E18-0087-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

CD226/DNAM-1 Antibody

E18-0087-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

CD226/DNAM-1 Antibody

AF0087 200ul
EUR 420

CD226/DNAM-1 Antibody

AF4778 200ul
EUR 540

CD226/DNAM-1 Antibody

AF4778-100ul 100ul
EUR 350

CD226/DNAM-1 Antibody

AF4778-200ul 200ul
EUR 450

CD226/DNAM-1 Antibody

AF4778-50ul 50ul
EUR 250

Cd226 Antibody / Dnam-1

RQ6373 100 ug
EUR 356.15
Description: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

CD226 Antibody / DNAM-1

RQ6841 100ug
EUR 356.15
Description: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

CD226/DNAM-1 Antibody

MBS8510593-005mg 0.05mg
EUR 235

CD226/DNAM-1 Antibody

MBS8510593-01mg 0.1mg
EUR 305

CD226/DNAM-1 Antibody

MBS8510593-01mLAF405M 0.1mL(AF405M)
EUR 465

CD226/DNAM-1 Antibody

MBS8510593-01mLAF546 0.1mL(AF546)
EUR 465

CD226/DNAM-1 Antibody

MBS8510593-01mLAF750 0.1mL(AF750)
EUR 465

CD226/DNAM-1 Antibody

MBS8529317-01mg 0.1mg
EUR 305

CD226/DNAM-1 Antibody

MBS8529317-01mLAF405L 0.1mL(AF405L)
EUR 465

CD226/DNAM-1 Antibody

MBS8529317-01mLAF405S 0.1mL(AF405S)
EUR 465

CD226/DNAM-1 Antibody

MBS8529317-01mLAF610 0.1mL(AF610)
EUR 465

CD226/DNAM-1 Antibody

MBS8529317-01mLAF635 0.1mL(AF635)
EUR 465

CD226/DNAM-1 Antibody

MBS9613485-005mL 0.05mL
EUR 245

CD226/DNAM-1 Antibody

MBS9613485-01mL 0.1mL
EUR 305

CD226/DNAM-1 Antibody

MBS9613485-02mL 0.2mL
EUR 365

CD226/DNAM-1 Antibody

MBS9613485-5x02mL 5x0.2mL
EUR 1495

CD226/DNAM-1 Antibody

MBS9503809-005mL 0.05mL
EUR 285

CD226/DNAM-1 Antibody

MBS9503809-01mL 0.1mL
EUR 385

CD226/DNAM-1 Antibody

MBS9503809-5x01mL 5x0.1mL
EUR 1590

CD226/DNAM-1 Antibody

MBS9509278-005mL 0.05mL
EUR 285

CD226/DNAM-1 Antibody

MBS9509278-01mL 0.1mL
EUR 385

CD226/DNAM-1 Antibody

MBS9509278-5x01mL 5x0.1mL
EUR 1590

CD226/DNAM-1 Antibody

AF0087-100ul 100ul
EUR 168
Description: WB,IF/ICC,ELISA(peptide)

CD226/DNAM-1 Antibody

AF0087-200ul 200ul
EUR 210
Description: WB,IF/ICC,ELISA(peptide)

CD226/DNAM-1 Antibody

MBS9600037-01mL 0.1mL
EUR 260

CD226/DNAM-1 Antibody

MBS9600037-02mL 0.2mL
EUR 305

CD226/DNAM-1 Antibody

MBS9600037-5x02mL 5x0.2mL
EUR 1220

Recombinant Human DNAM-1 Protein, Avi & His Tag

E40KMP1218 20ug
EUR 495

Recombinant Human DNAM-1 Protein, Avi & His Tag

E40KMP1892 20ug
EUR 495

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

AP76444 1mg
EUR 1879

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-10ug 10ug
EUR 151.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-1mg 1mg
EUR 1581.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-500ug 500ug
EUR 1155.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-50ug 50ug
EUR 333.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Rabbit Polyclonal Anti-CD226/DNAM-1 Antibody

TA347323 100 µg Ask for price

DNAM-1 Polyclonal Antibody

ABP53533-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

DNAM-1 Polyclonal Antibody

ABP53533-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

DNAM-1 Polyclonal Antibody

ABP53533-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

DNAM-1 Polyclonal Antibody

ABP53133-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

ABP53133-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

ABP53133-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

41787-100ul 100ul
EUR 302.4

DNAM-1 Polyclonal Antibody

41787-50ul 50ul
EUR 224.4

DNAM-1 Polyclonal Antibody

40846-100ul 100ul
EUR 302.4

DNAM-1 Polyclonal Antibody

40846-50ul 50ul
EUR 224.4

DNAM-1 Polyclonal Antibody

E040846 100μg/100μl
EUR 255
Description: Available in various conjugation types.

DNAM-1 Polyclonal Antibody

E041787 100μg/100μl
EUR 255
Description: Available in various conjugation types.

DNAM-1 Polyclonal Antibody

E20-75402 100ug
EUR 225
Description: Available in various conjugation types.

DNAM-1 Polyclonal Antibody

E20-71381 100ug
EUR 225
Description: Available in various conjugation types.

DNAM-1 Polyclonal Antibody

E44H06844 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

DNAM-1 Polyclonal Antibody

E44H01772 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

DNAM-1 Polyclonal Antibody

BT-AP02671-100ul 100ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02671-20ul 20ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02671-50ul 50ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02672-100ul 100ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The CD226 molecule mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02672-20ul 20ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The CD226 molecule mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02672-50ul 50ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The CD226 molecule mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

MBS9243428-01mL 0.1mL
EUR 415

DNAM-1 Polyclonal Antibody

MBS9243428-5x01mL 5x0.1mL
EUR 1841

DNAM-1 Polyclonal Antibody

MBS9246018-01mL 0.1mL
EUR 415

DNAM-1 Polyclonal Antibody

MBS9246018-5x01mL 5x0.1mL
EUR 1841

DNAM-1 Polyclonal Antibody

MBS9414684-005mL 0.05mL
EUR 245

DNAM-1 Polyclonal Antibody

MBS9414684-01mL 0.1mL
EUR 305

DNAM-1 Polyclonal Antibody

MBS9414684-5x01mL 5x0.1mL
EUR 1230

DNAM-1 Polyclonal Antibody

MBS9405445-005mL 0.05mL
EUR 245

DNAM-1 Polyclonal Antibody

MBS9405445-01mL 0.1mL
EUR 305

DNAM-1 Polyclonal Antibody

MBS9405445-5x01mL 5x0.1mL
EUR 1230

DNAM-1 Polyclonal Antibody

MBS8522362-01mg 0.1mg
EUR 305

DNAM-1 Polyclonal Antibody

MBS8522362-01mLAF405L 0.1mL(AF405L)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8522362-01mLAF405S 0.1mL(AF405S)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8522362-01mLAF610 0.1mL(AF610)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8522362-01mLAF635 0.1mL(AF635)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8526383-01mg 0.1mg
EUR 305

DNAM-1 Polyclonal Antibody

MBS8526383-01mLAF405L 0.1mL(AF405L)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8526383-01mLAF405S 0.1mL(AF405S)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8526383-01mLAF610 0.1mL(AF610)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8526383-01mLAF635 0.1mL(AF635)
EUR 465

DNAM-1 Polyclonal Antibody

MBS2534678-002mL 0.02mL
EUR 140

DNAM-1 Polyclonal Antibody

MBS2534678-006mL 0.06mL
EUR 180

DNAM-1 Polyclonal Antibody

MBS2534678-012mL 0.12mL
EUR 260

DNAM-1 Polyclonal Antibody

MBS2534678-02mL 0.2mL
EUR 405

DNAM-1 Polyclonal Antibody

MBS2534715-002mL 0.02mL
EUR 140

DNAM-1 Polyclonal Antibody

MBS2534715-006mL 0.06mL
EUR 180

DNAM-1 Polyclonal Antibody

MBS2534715-012mL 0.12mL
EUR 260

DNAM-1 Polyclonal Antibody

MBS2534715-02mL 0.2mL
EUR 405

DNAM-1 Polyclonal Antibody

UB-GEN-16420 100 ul
EUR 200

DNAM-1 Polyclonal Antibody

UB-GEN-16494 100 ul
EUR 200

Recombinant Human CD226/DNAM-1 Protein (C-Fc)

MBS2557338-001mg 0.01mg
EUR 155

Recombinant Human CD226/DNAM-1 Protein (C-Fc)

MBS2557338-005mg 0.05mg
EUR 285

Recombinant Human CD226/DNAM-1 Protein (C-Fc)

MBS2557338-5x005mg 5x0.05mg
EUR 1285

Recombinant Human CD226/DNAM-1 Protein (His Tag)

PKSH033728-10ug 10ug
EUR 92
Description: Human

Recombinant Human CD226/DNAM-1 Protein (His Tag)

PKSH033728-50ug 50ug
EUR 268
Description: Human

Recombinant Human CD226 / DNAM-1 Protein (His tag)

MBS2546178-01mg 0.1mg
EUR 685

Recombinant Human CD226 / DNAM-1 Protein (His tag)

MBS2546178-5x01mg 5x0.1mg
EUR 3080

ABflo® 488 Rabbit anti-Human DNAM-1/CD226 mAb

A23175 25μg
EUR 213.2
Description: Recombinant protein of human CD16.

ABflo® 647 Rabbit anti-Human DNAM-1/CD226 mAb

A23176 25μg
EUR 213.2
Description: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CES1 (P23141).

CD226/DNAM- 1 Antibody

ABF0087 100ug
EUR 325

Recombinant Human CD226 Antigen/DNAM-1/CD226 Protein (C-His)

MBS2557337-001mg 0.01mg
EUR 155

Recombinant Human CD226 Antigen/DNAM-1/CD226 Protein (C-His)

MBS2557337-005mg 0.05mg
EUR 285

Recombinant Human CD226 Antigen/DNAM-1/CD226 Protein (C-His)

MBS2557337-5x005mg 5x0.05mg
EUR 1285

Rat Monoclonal anti-Mouse CD226 (DNAM-1) Antibody

xAP-0583 100ug
EUR 280

Rat Monoclonal anti-Mouse CD226 (DNAM-1) Antibody

xAP-0584 100ug
EUR 280

Biotinylated Human DNAM-1 / CD226 Protein, Fc,Avitag™

DN1-H82F9 25ug
EUR 1722.7
Description: Biotinylated Human DNAM-1, Fc,Avitag (DN1-H82F9) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557).

Human CD226/DNAM-1 protein, His tag (Animal-Free)

PRP2038-100ug 100 μg
EUR 259
Description: Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells

Human CD226/DNAM-1 protein, His tag (Animal-Free)

PRP2038-10ug 10 μg
EUR 59
Description: Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells

Human CD226/DNAM-1 protein, His tag (Animal-Free)

PRP2038-1mg 1 mg
EUR 2369
Description: Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells

Human CD226/DNAM-1 protein, His tag (Animal-Free)

PRP2038-50ug 50 μg
EUR 139
Description: Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-001mg 0.01mg
EUR 115

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-005mg 0.05mg
EUR 160

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-01mg 0.1mg
EUR 230

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-1mg 1mg
EUR 1590

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-5x1mg 5x1mg
EUR 7110

dNAM

D100545 500mg
EUR 4500
Description: 1117893-19-2

Human DNAM-1 / CD226 Recombinant Protein His Tag Lyophilized

IHUDNAM1CD226RHISLY100UG each
EUR 851
Description: Human DNAM-1 / CD226 Recombinant Protein His Tag Lyophilized

Human DNAM-1/CD226 Recombinant Protein His Tag Lyophilized

MBS8431865-INQUIRE INQUIRE Ask for price

DNAM-1 Rabbit pAb

E2252268 100ul
EUR 225
Description: Available in various conjugation types.

DNAM-1 Rabbit pAb

MBS8540865-01mL 0.1mL
EUR 305

DNAM-1 Rabbit pAb

MBS8540865-01mLAF405L 0.1mL(AF405L)
EUR 565

DNAM-1 Rabbit pAb

MBS8540865-01mLAF405S 0.1mL(AF405S)
EUR 565

DNAM-1 Rabbit pAb

MBS8540865-01mLAF610 0.1mL(AF610)
EUR 565

DNAM-1 Rabbit pAb

MBS8540865-01mLAF635 0.1mL(AF635)
EUR 565

Recombinant Human CD226/DNAM-1 Protein (Fc Tag)(Active)

PKSH033729-10ug 10ug
EUR 92
Description: Human

Recombinant Human CD226/DNAM-1 Protein (Fc Tag)(Active)

PKSH033729-50ug 50ug
EUR 268
Description: Human

DNAM-1 (Phospho-Ser329) Antibody

A0843-100ul 100μl
EUR 217
Description: DNAM-1 (Phospho-Ser329) Rabbit Polyclonal Antibody

DNAM-1 (Phospho-Ser329) Antibody

A0843-50ul 50μl
EUR 143.5
Description: DNAM-1 (Phospho-Ser329) Rabbit Polyclonal Antibody

Recombinant Human CD226/DNAM-1 Protein (His Tag)(Active)

PKSH031523-100ug 100ug
EUR 732
Description: Human

DNAM-1 Rabbit Polyclonal Antibody

ES4532-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against DNAM-1 from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

DNAM-1 Rabbit Polyclonal Antibody

ES4532-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against DNAM-1 from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

DNAM-1 Rabbit Polyclonal Antibody

ES4132-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against DNAM-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

DNAM-1 Rabbit Polyclonal Antibody

ES4132-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against DNAM-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Alexa Fluor® 647 anti-mouse CD226 (DNAM-1)

E16FMK226-100U 100 μg
EUR 1278.33
Description: Available in various conjugation types.

DNAM-1 Polyclonal Conjugated Antibody

C40846 100ul
EUR 476.4

DNAM-1 Polyclonal Conjugated Antibody

MBS9449752-01mLAF350 0.1mL(AF350)
EUR 480

DNAM-1 Polyclonal Conjugated Antibody

MBS9449752-01mLAF405 0.1mL(AF405)
EUR 480

DNAM-1 Polyclonal Conjugated Antibody

MBS9449752-01mLAF488 0.1mL(AF488)
EUR 480

DNAM-1 Polyclonal Conjugated Antibody

MBS9449752-01mLAF555 0.1mL(AF555)
EUR 480

DNAM-1 Polyclonal Conjugated Antibody

MBS9449752-01mLBiotin 0.1mL(Biotin)
EUR 480

DNAM-1 Recombinant Protein

96-863 0.1 mg
EUR 588.3
Description: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

DNAM-1 Recombinant Protein

96-864 0.1 mg
EUR 588.3
Description: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

Nonetheless, the results and molecular mechanisms of C3C12PPD on non-small cell lung most cancers (NSCLC) stay unclear. In line with earlier research, we hypothesized ginsenoside C3C12PPD may inhibit the tumor progress of NSCLC by focusing on proliferation, migration and angiogenesis.

 

 

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