Elongation factor P is required for EII Glc translation in Corynebacterium glutamicum due to an essential polyproline motif

Elongation factor P is required for EII Glc translation in Corynebacterium glutamicum due to an essential polyproline motif

Translating ribosomes require elongation issue P (EF-P) to include consecutive prolines (XPPX) into nascent peptide chains. The proteome of Corynebacterium glutamicum ATCC 13032 accommodates a complete of 1,468 XPPX motifs, a lot of that are present in proteins concerned in main and secondary metabolism. We present right here that synthesis of EIIGlc , the glucose-specific permease of the phosphoenolpyruvate (PEP): sugar phosphotransferase system (PTS) encoded by ptsG, is strongly depending on EF-P, as an efp deletion mutant grows poorly on glucose as sole carbon supply.

The quantity of EIIGlc is strongly lowered on this mutant, which consequently ends in a decrease charge of glucose uptake. Strikingly, the XPPX motif is crucial for the exercise of EIIGlc , and substitution of the prolines results in inactivation of the protein. Lastly, translation of GntR2, a transcriptional activator of ptsG, can also be depending on EF-P. Nonetheless, its lowered quantity within the efp mutant may be compensated for by different regulators. These outcomes reveal for the primary time a translational bottleneck involving manufacturing of the key glucose transporter EIIGlc , which has implications for future pressure engineering methods.

ZmMPK6 and ethylene signaling negatively regulate the buildup of anti-insect metabolites DIMBOA and DIMBOA-Glc in maize inbred line A188

2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and DIMBOA-glucoside (DIMBOA-Glc) are anti-insect benzoxazinoids in maize. But little or no is understood about how they’re regulated. Reverse genetics, kinase exercise evaluation, phytohormone and DIMBOA/DIMBOA-Glc quantification, bioassays, and transcriptome evaluation had been employed to review the perform of ZmMPK6, a mitogen-activated protein kinase, in maize response to herbivory. ZmMPK6 was quickly activated by wounding and simulated herbivory.

Ethylene complementation experiment revealed that ZmMPK6 repressed the buildup of DIMBOA/DIMBOA-Glc in an ethylene-dependent method. Transcriptome evaluation revealed that ZmMPK6 may meditate the transcription of BX1 by controlling a MYB transcription issue that’s doubtless positioned within the ethylene signaling pathway, and moreover, ZmMPK6 and ethylene signaling additionally particularly and generally regulate the transcription of different benzoxazinoid biosynthetic genes.

We additionally present that completely different maize strains have very completely different responses to simulated herbivory when it comes to ZmMPK6 activation, ethylene emission, and benzoxazinoid ranges. These outcomes uncover that ZmMPK6 and ethylene pathway are novel repressors of DIMBOA/DIMBOA-Glc and supply new perception into the regulatory mechanisms underlying these two pathways. Silencing ZmMPK6 in maize A188 compromised simulated herbivory-induced ethylene ranges however not these of jasmonic acid or salicylic acid, and the ZmMPK6-silenced vegetation exhibited elevated DIMBOA/DIMBOA-Glc and bug resistance.

Elongation factor P is required for EII Glc translation in Corynebacterium glutamicum due to an essential polyproline motif

Evaluation of the Rest-Enhancing Properties of a Nitroxide-Based mostly Distinction Agent TEEPO-Glc with In Vivo Magnetic Resonance Imaging.

Magnetic resonance imaging examinations are continuously carried out utilizing distinction brokers to enhance the picture high quality. Virtually all clinically used distinction brokers are primarily based on paramagnetic metals and lack in selectivity and specificity. A bunch of secure natural radicals, nitroxides, has raised curiosity as new metal-free distinction brokers for MRI. Their buildings can simply be modified to include completely different functionalities.

Within the current examine, a secure nitroxide TEEPO was linked to a glucose moiety (Glc) to assemble a water-soluble, doubtlessly tumor-targeting compound with contrast-enhancing capability. The power was assessed with in vivo MRI experiments. The constructed TEEPO-Glc agent proved to shorten the T1 rest time in tumor, whereas the T1 time in wholesome mind tissue remained the identical. The outcomes point out the potential of TEEPO-Glc as a useful addition to the rising area of metal-free distinction enhancement in MRI-based diagnostics.

SPION-Embellished Exosome Delivered BAY55-9837 Focusing on the Pancreas by means of Magnetism to Enhance the Blood GLC Response.

BAY55-9837, a possible therapeutic peptide within the remedy of kind 2 diabetes mellitus (T2DM), is able to inducing glucose (GLC)-dependent insulin secretion. Nonetheless, the therapeutic good thing about BAY55-9837 is restricted by its brief half-life, lack of focusing on capability, and poor blood GLC response. How you can enhance the blood GLC response of BAY55-9837 is an present drawback that must be solved. On this examine, a way for getting ready BAY55-9837-loaded exosomes coupled with superparamagnetic iron oxide nanoparticle (SPIONs) with pancreas islet focusing on exercise and an enhanced blood GLC response with the assistance of an exterior magnetic power (MF) is demonstrated.

The plasma half-life of BAY55-9837 loaded in exosome-SPION is 27-fold longer than that of BAY55-9837. The energetic focusing on property of SIPONs allows BAY-exosomes to achieve a positive focusing on property, which improves the BAY55-9837 blood GLC response capability with the assistance of an exterior MF. In vivo research present that BAY-loaded exosome-based car supply enhances pancreas islet focusing on beneath an exterior MF and markedly will increase insulin secretion, thereby resulting in the alleviation of hyperglycemia. The continual administration of BAY-exosome-SPION/MF considerably improves glycosylated hemoglobin and lipid profiles. BAY-exosome-SPION/MF perhaps a promising candidate for a peptide drug service for T2DM with a greater blood GLC response.

The consequences and mechanisms of a biosynthetic ginsenoside 3β,12β-Di-O-Glc-PPD on non-small cell lung most cancers.

A biosynthetic ginsenoside, 3-O-β-D-glucopyranosyl-12-O-β-D-glucopyranosyl-dammar-24-ene-3β, 12β, 20S-triol (C3C12PPD), confirmed antitumor exercise towards many tumor cells in vitro, particularly had higher anti-lung most cancers exercise than Rg3 in vitro and in vivo.

Anti-Phospho-DNAM-1 (S329) antibody

STJ91074 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-DNAM-1 (S329).

CD226/DNAM-1 Antibody

AF4778 200ul
EUR 376
Description: CD226/DNAM-1 Antibody detects endogenous levels of CD226/DNAM-1.

CD226/DNAM-1 Antibody

AF0087 200ul
EUR 304
Description: CD226/DNAM-1 antibody detects endogenous levels of total CD226/DNAM-1.

DNAM-1 Polyclonal Antibody

ES4132-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against DNAM-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

DNAM-1 Polyclonal Antibody

ES4132-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against DNAM-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

DNAM-1 Polyclonal Antibody

ES4532-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against DNAM-1 from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

DNAM-1 Polyclonal Antibody

ES4532-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against DNAM-1 from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

CD226 / DNAM-1 Antibody

20-abx119383
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

DNAM-1 Polyclonal Antibody

ABP53133-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human DNAM-1
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

ABP53133-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human DNAM-1
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

ABP53133-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human DNAM-1
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

ABP53533-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

DNAM-1 Polyclonal Antibody

ABP53533-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

DNAM-1 Polyclonal Antibody

ABP53533-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

CD226/DNAM- 1 Antibody

ABF0087 100 ug
EUR 438

DNAM-1 Polyclonal Antibody

41787-100ul 100ul
EUR 252

DNAM-1 Polyclonal Antibody

41787-50ul 50ul
EUR 187

DNAM-1 Polyclonal Antibody

40846-100ul 100ul
EUR 252

DNAM-1 Polyclonal Antibody

40846-50ul 50ul
EUR 187

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

CD226/DNAM-1 Blocking Peptide

AF4778-BP 1mg
EUR 195

DNAM-1 Polyclonal Conjugated Antibody

C40846 100ul
EUR 397

CD226/DNAM-1 Blocking Peptide

AF0087-BP 1mg
EUR 195

Phospho-CD226/DNAM-1 (Ser329) Antibody

AF4478 200ul
EUR 376
Description: CD226/DNAM-1 (Phospho-Ser329) Antibody detects endogenous levels of CD226/DNAM-1 only when phosphorylated at Ser329.

DNAM-1 (phospho Ser329) Polyclonal Antibody

ES4531-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against DNAM-1 (phospho Ser329) from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

DNAM-1 (phospho Ser329) Polyclonal Antibody

ES4531-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against DNAM-1 (phospho Ser329) from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

DNAM-1 (phospho Ser329) Polyclonal Antibody

ABP53532-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human DNAM-1 around the phosphorylation site of S329
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 phospho Ser329) from Human, Mouse, Monkey. This DNAM-1 phospho Ser329) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the phosphorylation site of S329

DNAM-1 (phospho Ser329) Polyclonal Antibody

ABP53532-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human DNAM-1 around the phosphorylation site of S329
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 phospho Ser329) from Human, Mouse, Monkey. This DNAM-1 phospho Ser329) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the phosphorylation site of S329

DNAM-1 (phospho Ser329) Polyclonal Antibody

ABP53532-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human DNAM-1 around the phosphorylation site of S329
  • Applications tips:
Description: A polyclonal antibody for detection of DNAM-1 phospho Ser329) from Human, Mouse, Monkey. This DNAM-1 phospho Ser329) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the phosphorylation site of S329

DNAM-1 (Phospho-Ser329) Polyclonal Antibody

12361-100ul 100ul
EUR 252

DNAM-1 (Phospho-Ser329) Polyclonal Antibody

12361-50ul 50ul
EUR 187

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Phospho-CD226/DNAM-1 (Ser329) Blocking Peptide

AF4478-BP 1mg
EUR 195

Human DNA methyltransferase(DNAM)ELISA Kit

GA-E1991HM-48T 48T
EUR 289

Human DNA methyltransferase(DNAM)ELISA Kit

GA-E1991HM-96T 96T
EUR 466

Human DNA methyltransferase,DNAM ELISA Kit

201-12-1975 96 tests
EUR 440
  • This DNA methyltransferase ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human DNA methyltransferase(DNAM)ELISA Kit

QY-E04972 96T
EUR 361

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-10ug 10ug
EUR 126
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-1mg 1mg
EUR 1318
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-500ug 500ug
EUR 963
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-50ug 50ug
EUR 278
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-10ug 10ug
EUR 126
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-1mg 1mg
EUR 1318
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-500ug 500ug
EUR 963
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-50ug 50ug
EUR 278
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

DNAM-1 (Phospho-Ser329) Polyclonal Polyclonal Conjugated Antibody

C12361 100ul
EUR 397

Recombinant DNAM-1 Protein (Glu 19-Phe 252)

VAng-1466Lsx-100g 100 µg
EUR 1013
Description: Cynomolgus DNAM-1 is expressed in HEK 293 cells. (Uniprot ID: A0A2K5W1Z6-1)

Recombinant DNAM-1 Protein (Glu 19-Phe 252)

VAng-1466Lsx-1mg 1 mg
EUR 6402
Description: Cynomolgus DNAM-1 is expressed in HEK 293 cells. (Uniprot ID: A0A2K5W1Z6-1)

Anti-Apaf-1 (human) Monoclonal Antibody (2E12)

M00889-1 100ug
EUR 432
Description: Rat Monoclonal Apaf-1 (human) Antibody (2E12). Validated in ELISA, IP, IF, WB and tested in Human.

Recombinant DNAM-1 Protein (Glu 19-Asn 247) [Fc]

VAng-1463Lsx-100g 100 µg
EUR 738
Description: Human DNAM-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_006557)

Recombinant DNAM-1 Protein (Glu 19-Asn 247) [Fc]

VAng-1463Lsx-1mg 1 mg
EUR 4174
Description: Human DNAM-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_006557)

Recombinant DNAM-1 Protein (Glu 19-Asn 247) [His]

VAng-1465Lsx-100g 100 µg
EUR 738
Description: Human DNAM-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_006557)

Recombinant DNAM-1 Protein (Glu 19-Asn 247) [His]

VAng-1465Lsx-1mg 1 mg
EUR 4174
Description: Human DNAM-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_006557)

Rat DNA methyltransferase(DNAM)ELISA Kit

GA-E0805RT-48T 48T
EUR 317

Rat DNA methyltransferase(DNAM)ELISA Kit

GA-E0805RT-96T 96T
EUR 496

Rat DNA methyltransferase(DNAM)ELISA Kit

QY-E10847 96T
EUR 361

Mouse DNA methyltransferase(DNAM)ELISA Kit

QY-E20479 96T
EUR 361

Anti-PARP-1 Antibody

A00122-1 100ul
EUR 397
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.

Anti-Presenilin 1 Antibody

A00138-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat.

Anti-PAI-1 Antibody

A00637-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat.

Anti-Flk-1 Antibody

A00901-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse.

Anti-EDG-1 Antibody

A01502-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat.

Anti-ROBO-1 Antibody

A01530-1 100ug
EUR 455
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Bag-1 Antibody

A02423-1 50 ul
EUR 397
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat.

Anti-TUB 1 Antibody

A02917-1 100ug/vial
EUR 294

Anti-Dok-1 Antibody

A03039-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat.

Anti-TFIIIB90-1 Antibody

A03761-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse.

Anti-Atrophin-1 Antibody

A03828-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-CNG-1 Antibody

A05494-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Periphilin 1 Antibody

A06996-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse.

Anti-Lyl-1 Antibody

A07491-1 100ul
EUR 397
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GLI-1 Antibody

A07972-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Cerebellin 1 Antibody

A09176-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-DOC-1 Antibody

A09467-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse.

Anti-NPDC-1 Antibody

A12846-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat.

Anti-P-glycoprotein (human) Monoclonal Antibody (JSB-1)

M00049-1 125ug
EUR 586
Description: Mouse Monoclonal P-glycoprotein (human) Antibody (JSB-1). Validated in IF and tested in Human.

Recombinant Mouse DNAX Accessory Molecule-1/DNAM-1/CD226 (C-6His)

CS07-10ug 10ug
EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse DNAX Accessory Molecule-1/DNAM-1/CD226 (C-6His)

CS07-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse DNAX Accessory Molecule-1/DNAM-1/CD226 (C-6His)

CS07-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse DNAX Accessory Molecule-1/DNAM-1/CD226 (C-6His)

CS07-50ug 50ug
EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Anti-TNF Receptor 1 Antibody

A00294-1 200ug
EUR 522
Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.

Anti-Galectin 1/Lgals1 Antibody

A00470-1 100ug/vial
EUR 334

Anti-LOX-1/OLR1 Antibody

A00760-1 100ug/vial
EUR 294

Anti-Syndecan-1/SDC1 Antibody

A00991-1 100ug/vial
EUR 294

Anti-IRAK-1/IRAK1 Antibody

A01021-1 100ug/vial
EUR 334

Anti-Neurexin 1/NRXN1 Antibody

A01490-1 100ug/vial
EUR 334

Anti-Hexokinase 1/HK1 Antibody

A01504-1 100ug/vial
EUR 334

Anti-Synaptotagmin 1/SYT1 Antibody

A02314-1 100ug/vial
EUR 334

Anti-Syntenin-1 Monoclonal Antibody

A02475-1 100ul
EUR 397
Description: Mouse Monoclonal Antibody for Syntenin-1 Antibody (SDCBP) detection. Tested with WB in Human, Rat, Dog, Pig.

Anti-Dsg1/Desmoglein 1 Antibody

A02655-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Dsg1 Antibody (DSG1) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-CAF-1 p150 Antibody

A02732-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for CAF-1 p150 Antibody (CHAF1A) detection. Tested with WB in Human, Mouse.

Anti-Talin 1/TLN1 Antibody

A02859-1 100ug/vial
EUR 334

Anti-Islet 1/ISL1 Antibody

A02969-1 100ug/vial
EUR 334

Anti-Musashi 1/Msi1 Antibody

A05052-1 100ug/vial
EUR 334

Anti-CHST8/Galnac4St 1 Antibody

A10989-1 100ul
EUR 397
Description: Rabbit Polyclonal CHST8/Galnac4St 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Pyrophosphatase 1/PPA1 Antibody

A07485-1 100ug/vial
EUR 334

Anti-TCP-1 eta Antibody

A08169-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TCP-1 eta Antibody (CCT7) detection. Tested with WB in Human, Mouse, Rat.

Anti-Relaxin 1/RLN1 Antibody

A08367-1 100ug/vial
EUR 334

Anti-TCP-1 zeta Antibody

A09373-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TCP-1 zeta Antibody (CCT6A) detection.tested for WB in Human, Mouse, Rat.

Anti-Galectin 1/LGALS1 Antibody

PB9240-1 100ug/vial
EUR 334

Anti-Presenilin 1 Monoclonal Antibody

M00138-1 100ug
EUR 397
Description: Rabbit Monoclonal Presenilin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Galectin 1 Monoclonal Antibody

M00470-1 100ug
EUR 397
Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-DJ-1 Monoclonal Antibody

M00757-1 100ul
EUR 397
Description: Mouse Monoclonal DJ-1 Antibody. Validated in IHC, WB and tested in Bovine, Human.

Anti-Enolase 1 Monoclonal Antibody

M01250-1 100ul
EUR 397
Description: Anti-Enolase 1 Monoclonal Antibody tested in WB, IF, ICC, IHC, reactive to Human, rat, mouse, cow, pig, horse

Anti-Dynamin 1 Monoclonal Antibody

M02536-1 100ug
EUR 397
Description: Rabbit Monoclonal Dynamin 1 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-Esrp-1 Monoclonal Antibody

M06068-1 100uL
EUR 443
Description: Mouse Monoclonal Esrp-1 Antibody. Validated in WB and tested in Human.

Anti-Angiopoietin 1/ANGPT1 Antibody

PA1333-1 100ug/vial
EUR 334

Anti-TTF-1

DB-089-1 1 ml
EUR 750
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Recombinant DNAM-1 Protein (Glu 19-Asn 247) [Fc] [Avi]

VAng-1464Lsx-200g 200 µg
EUR 3844
Description: Biotinylated Human DNAM-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: NP_006557)

Recombinant DNAM-1 Protein (Glu 19-Asn 247) [Fc] [Avi]

VAng-1464Lsx-25g 25 µg
EUR 1013
Description: Biotinylated Human DNAM-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: NP_006557)

Anti-HLA-G (human) Monoclonal Antibody (MEM-G/1)

M01235-1 100ug
EUR 397
Description: Mouse Monoclonal HLA-G (human) Antibody (MEM-G/1). Validated in IHC, WB and tested in Human.

Anti-HO-1 Monoclonal Antibody (HO-1-2)

M00253-1 1mg
EUR 397
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat.

Anti-HIF-1 alpha/HIF1A Antibody

A00013-1 100ug/vial
EUR 294

Anti-Cleaved-Notch 1 (V1754) Antibody

A00033-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Cleaved-Notch 1 (V1754) Antibody (NOTCH1) detection.tested for WB in Human, Mouse, Rat.

Anti-HDAC-1 (C-terminus) Antibody

A00256-1 100uL
EUR 443
Description: Rabbit Polyclonal HDAC-1 (C-terminus) Antibody. Validated in IF, IHC, WB and tested in Human.

Anti-VEGF Receptor 1/FLT1 Antibody

A00534-1 100ug/vial
EUR 294

Anti-Liver Carboxylesterase 1/CES1 Antibody

A01741-1 100ug/vial
EUR 334

Anti-EBP50/NHERF-1/SLC9A3R1 Antibody

A02427-1 100ug/vial
EUR 334

Anti-IL1R2/Il 1 Rii Antibody

A03106-1 1 ml
EUR 397
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human.

Anti-Hyaluronan synthase 1/HAS1 Antibody

A04784-1 100ug/vial
EUR 334

Anti-CELSR3/Flamingo Homolog 1 Antibody

A07204-1 100ul
EUR 397
Description: Rabbit Polyclonal CELSR3/Flamingo Homolog 1 Antibody. Validated in IF and tested in Human, Mouse, Rat.

Anti-LPCAT2/Acyltransferase Like 1 Antibody

A07471-1 100ul
EUR 397
Description: Rabbit Polyclonal LPCAT2/Acyltransferase Like 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Sumo 1 Rabbit Monoclonal Antibody

M00631-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Sumo 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Cytokeratin 1 Rabbit Monoclonal Antibody

M01639-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Cytokeratin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Mitofusin 1 Antibody (monoclonal, 3H3)

M02172-1 100ug/vial
EUR 294

Anti-Phospho-Beclin-1 (Ser295) Antibody

P00327-1 100ul
EUR 398
Description: Rabbit Polyclonal Phospho-Beclin-1 (Ser295) Antibody. Validated in WB and tested in Human.

Anti-Phospho-Raf-1 (Ser642) Antibody

P00446-1 100ul
EUR 398
Description: Rabbit Polyclonal Phospho-Raf-1 (Ser642) Antibody. Validated in WB and tested in Human, Rat.

Anti-Integrin alpha 1/ITGA1 Antibody

PA1045-1 100ug/vial
EUR 334

Anti-Caspase-1(P20)/CASP1 Antibody

PA1440-1 100ug/vial
EUR 294

Anti-VEGF Receptor 1/FLT1 Antibody

PA1966-1 100ug/vial
EUR 294

Anti-CCR4 (human) Antibody

A00755-1 200ug
EUR 397
Description: Goat Polyclonal CCR4 (human) Antibody. Validated in IF, IHC and tested in Human.

Anti-EBV/LMP-1

DB-060-1 1 ml
EUR 750
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-EBV/LMP-1

DB-061-1 1 ml
EUR 750
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif

AXMIR-1 10 reactions
EUR 438
  • Category: Exosome

Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378

M04431-1 100uL
EUR 385
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human

Anti-E74 like factor 1/ELF1 Antibody

A03187-1 100ug/vial
EUR 294

Anti-GABA B Receptor 1/GABBR1 Antibody

A07297-1 100ug/vial
EUR 294

Anti-Vangl1/Vang Like Protein 1 Antibody

A07587-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Vangl1 Antibody (VANGL1) detection. Tested with WB in Human, Mouse.

Anti-HMGB1/Hmg 1 Rabbit Monoclonal Antibody

M00066-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal HMGB1/Hmg 1 Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-p27 KIP 1 Rabbit Monoclonal Antibody

M00173-1 100ug/vial
EUR 397
Description: Anti-p27 KIP 1 Rabbit Monoclonal Antibody tested for Flow Cytometry, IP, IF, IHC, ICC, WB in Human, Rat

Anti-Caveolin-1/CAV1 Antibody (monoclonal, 12C7)

M00179-1 100ug/vial
EUR 334

Anti-MHC class 1 Rabbit Monoclonal Antibody

M00194-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal MHC class 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human.

Anti-Integrin beta 1 Rabbit Monoclonal Antibody

M00772-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Integrin beta 1 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-ARG1/Arginase 1 Rabbit Monoclonal Antibody

M01106-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal ARG1/Arginase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

Anti-MLANA/Mart 1 Rabbit Monoclonal Antibody

M02033-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal MLANA/Mart 1 Antibody. Validated in IF, WB and tested in Human.

Anti-TCP-1α Monoclonal Antibody (91a)

M02389-1 200ug
EUR 498
Description: Rat Monoclonal TCP-1α Antibody (91a). Validated in Flow Cytometry, IP, IF, WB and tested in Human, Mouse, Rat.

Anti-DSG1/Desmoglein 1 Rabbit Monoclonal Antibody

M02655-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal DSG1/Desmoglein 1 Antibody. Validated in IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-Musashi 1/Msi1 Antibody (monoclonal, 2B9)

M05052-1 100ug/vial
EUR 334

Anti-Visinin-like Protein 1 Monoclonal Antibody

M06959-1 100ul
EUR 397
Description: Mouse Monoclonal Visinin-like Protein 1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Phospho-Glycogen Synthase 1 (S645) Antibody

P03512-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Phospho-Glycogen Synthase 1 (S645) Antibody (GYS1) detection.tested for WB in Human, Mouse, Rat.

Anti-Angiotensin Converting Enzyme 1/ACE Antibody

PA2196-1 100ug/vial
EUR 334

miRZip-1 anti-miR-1 microRNA construct

MZIP1-PA-1 Bacterial Streak
EUR 684
  • Category: MicroRNA Tools

Anti-EMA (CD227, Mucin-1)

DB-048-1 1 ml
EUR 450
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-Mitochondrial Pyruvate dehydrogenase kinase 1/PDK1 Antibody

A01268-1 100ug/vial
EUR 334

Anti-AFP/Alpha 1 Fetoprotein Rabbit Monoclonal Antibody

M00522-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal AFP/Alpha 1 Fetoprotein Antibody. Validated in IP, IF, WB and tested in Human.

Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody

M00720-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal SERPINA1/Alpha 1 Antitrypsin Antibody. Validated in IP, IF, WB and tested in Human.

Anti-GPX1/Glutathione Peroxidase 1 Rabbit Monoclonal Antibody

M01019-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal GPX1/Glutathione Peroxidase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

Anti-BAG-1 Rabbit Monoclonal Antibody, Clone#RM356

M02423-1 100uL
EUR 385
Description: Anti-BAG-1 Rabbit Monoclonal Antibody, Clone#RM356 tested in WB, IHC, reactive to Human

XStamp Pro anti-PD-1 EV Targeting Kit

XSTP915A-1 10 rxn
EUR 805
  • Category: Exosome

Anti-Human IgG

DB-173-1 1 ml
EUR 613
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-Human IgG

DB-174-1 1 ml
EUR 613
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-Adiponectin Receptor 2 (human) Antibody

A02218-1 200ug
EUR 498
Description: Goat Polyclonal Adiponectin Receptor 2 (human) Antibody. Validated in IF, IHC and tested in Human.

Anti-Human Ki-67 Monoclonal Antibody

M00254-1 100ul
EUR 397
Description: Mouse Monoclonal Human Ki-67 Antibody. Validated in WB and tested in Human.

Anti-CEACAM1 (human) Monoclonal Antibody (GM8G5)

M00923-1 100ug
EUR 609
Description: Mouse Monoclonal CEACAM1 (human) Antibody (GM8G5). Validated in Flow Cytometry, IHC and tested in Human.

Anti-FasL (human) Monoclonal Antibody (5G51)

M00925-1 100ug
EUR 559
Description: Mouse Monoclonal FasL (human) Antibody (5G51). Validated in Cell Function, Flow Cytometry and tested in Human.

Anti-Human IgM Rabbit Monoclonal Antibody

M07469-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Human IgM Antibody. Validated in IP, WB and tested in Human.

CF633 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20250-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

CF640R Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20251-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

CF647 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20252-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

CF680 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20253-1 50uL
EUR 161
Description: Minimum order quantity: 1 unit of 50uL

CF770 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20254-1 50uL
EUR 161
Description: Minimum order quantity: 1 unit of 50uL

CF543 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20325-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

CF350 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20245-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

CF488A Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20246-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

CF555 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20247-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

CF568 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20248-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

CF594 Goat Anti-Mouse IgG1 (γ1), 2mg/mL

20249-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL

Anti-Phospho-AMPK alpha 1 (S496) Rabbit Monoclonal Antibody

P00994-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Phospho-AMPK alpha 1 (S496) Antibody. Validated in IP, IF, WB and tested in Human.

Monoclonal Anti-Human PSA/ACT complex IgG # 1 aff pure

PSA15-M-1 1000 ug
EUR 773

Hemokinin 1 (human)

B5318-1 1 mg
EUR 340

Endothelin-1 (1-15), amide, human

A1111-1 1 mg
EUR 722
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis.

Haptoglobin, (Phenotype 1-1) Human Plasma

7536-1
EUR 321

Anti-PIKFyve

B5524-.1 100 ug
EUR 664

Anti-HtrA2/Omi (human) Monoclonal Antibody (196C429)

M01941-1 100ug
EUR 432
Description: Mouse Monoclonal HtrA2/Omi (human) Antibody (196C429). Validated in IHC, WB and tested in Human.

Anti-HIF-1 alpha (HIF1A) Rabbit Monoclonal Antibody, Clone#RM242

M00013-1 100ul
EUR 375
Description: Anti-HIF-1 alpha (HIF1A) Rabbit Monoclonal Antibody, Clone#RM242 tested in WB, IHC, reactive to Human

BNP (1-32), human

A1105-1 1 mg
EUR 177
Description: Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).

IGF-1, human recombinant

P1016-.1 100 µg
EUR 763
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

Nonetheless, the results and molecular mechanisms of C3C12PPD on non-small cell lung most cancers (NSCLC) stay unclear. In line with earlier research, we hypothesized ginsenoside C3C12PPD may inhibit the tumor progress of NSCLC by focusing on proliferation, migration and angiogenesis.

 

 

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