Doped graphite-like coating (GLC) has aroused nice curiosity as one of the crucial promising protecting supplies in marine functions. Nonetheless, there’s a lack of systematic analysis on the tribocorrosion and antifouling efficiency of doped GLC coatings in harsh marine environments. Herein, a multifunctional (Cr, Cu)-GLC coating with mixed antifouling and tribocorrosion properties was ready through a magnetron sputtering methodology. The experimental outcomes point out that the resultant coatings modified from a dense construction to a free columnar construction with the increment of Cr and Cu doping quantity.
On the similar time, the hardness of the coating steadily decreases, however the contact angle between coating and seawater steadily will increase. The algae adhesion check reveal that the algae density on the floor of the (Cr, Cu)-GLC coating decreases from about 565 to 70/mm2 as the quantity of doping elevated. Nonetheless, quite the opposite, the friction coefficient of the coating below OCP situation will increase from 0.06 to about 0.35. General, the gentle doped (Cr, Cu)-GLC coating reveals the very best complete properties, combining antifouling and tribocorrosion properties. The corresponded mechanisms are mentioned when it comes to the coating microstructure, antifouling, and tribocorrosion conduct.
The corrosion and tribology are all carefully associated to the interface/floor of supplies, that are extraordinarily vital for the mechanical elements utilized in harsh marine environments. On this work, we fabricated Cr/graphite-like carbon (GLC) multilayered movies with totally different modulation durations on the 316L stainless steels by direct present magnetron sputtering. Tribocorrosion assessments in synthetic seawater present that the tribocorrosion resistance of the Cr/GLC movies is improved because the modulation interval decreases from 1000 to 333 nm after which drastically drops with additional lowering to 250 nm. By taking a top-layer thickening technique for the Cr/GLC movie with 250 nm modulation interval, the tribocorrosion efficiency is considerably enhanced. The corresponded mechanisms are mentioned when it comes to the movie construction and electrochemical corrosion conduct.
Immunomodulatory glc/man-directed Dolichos lablab lectin (DLL) evokes anti-tumour response in vivo by counteracting angiogenic gene expressions.
Neovascularization and jeopardized immunity has been critically emphasised for the institution of malignant development. Lectins are the varied class of carbohydrate interacting proteins, having nice potential as immunopotentiating and anti-cancer brokers. The current investigation sought to exhibit the anti-proliferative exercise of Dolichos lablab lectin (DLL) encompassing immunomodulatory attributes. DLL particular to glucose and mannose carbohydrate moieties has been purified to homogeneity from the widespread dietary legume D. lablab. Outcomes elucidated that DLL agglutinated blood cells non-specifically and displayed placing mitogenicity to human and murine lymphocytes in vitro with interleukin (IL)-2 manufacturing.
The DLL-conditioned medium exerted cytotoxicity in direction of malignant cells and neoangiogenesis in vitro. Equally, in-vivo anti-tumour investigation of DLL elucidated the regressed proliferation of ascitic and strong tumour cells, which was paralleled with blockade of tumour neovasculature. DLL-treated mice confirmed an up-regulated immunoregulatory cytokine IL-2 in distinction to severely declined ranges in management mice. Mechanistic validation revealed that DLL has abrogated the microvessel formation by weakening the proangiogenic alerts, particularly nuclear issue kappa B (NF-κB), hypoxia inducible issue 1α (HIF-1 α), matrix metalloproteinase (MMP)-2 and 9 and vascular endothelial development issue (VEGF) in malignant cells resulting in tumour regression.
In abstract, it’s evident that the dietary lectin DLL probably dampens the malignant institution by mitigating neoangiogenesis and immune shutdown. For the primary time, to our data, this research illustrates the important position of DLL as an immunostimulatory and anti-angiogenic molecule in most cancers therapeutics.
Alteration of cell wall polysaccharides by way of transgenic expression of UDP-Glc 4-epimerase-encoding genes in potato tubers.
Uridine diphosphate (UDP)-glucose 4-epimerase (UGE) catalyzes the conversion of UDP-glucose to UDP-galactose. Cell wall supplies from the cv. Kardal (wild-type, background) and two UGE transgenic traces (UGE 45-1 and UGE 51-16) have been remoted and fractionated. The galactose (Gal) content material (mg/100g tuber) from UGE 45-1 transgenic line was 38% greater than that of wild-type, and resulted in longer pectin facet chains. The Gal content material current in UGE 51-16 was 17% decrease than that of wild-type, though most pectin populations maintained the identical degree of Gal.
Each UGE transgenic traces confirmed unexpectedly a lower in acetylation and a rise in methyl-esterification of pectin. Each UGE transgenic traces confirmed related proportions of homogalacturonan and rhamnogalacturonan I inside pectin spine because the wild-type, apart from the calcium-bound pectin fraction exhibiting comparatively much less rhamnogalacturonan I. Subsequent to pectin modification, xyloglucan populations from each transgenic traces have been altered leading to totally different XSGG and XXGG proportion compared to wild-type.
Mode of Interplay of the Sign-Transducing Protein EIIA(Glc) with the Maltose ABC Transporter within the Technique of Inducer Exclusion.
Enzyme IIA(Glc) (EIIA(Glc)) of the phosphoenolpyruvate phosphotransferase system for the uptake of glucose in Escherichia coli and Salmonella inhibits the maltose ATP-binding cassette transporter (MalE-FGK2) by interplay with the nucleotide-binding and -hydrolyzing subunit MalK, a course of termed inducer exclusion. We’ve got investigated binding of EIIA(Glc) to the MalK dimer by cysteine cross-linking in proteoliposomes. The outcomes show that the binding website I of EIIA(Glc) is contacting the N-terminal subdomain of MalK whereas the binding website II is comparatively near the C-terminal (regulatory) subdomain, in settlement with a crystal construction [ Chen , S. , Oldham , M. L. , Davidson , A. L. , and Chen , J. ( 2013 ) Nature 499 , 364 – 368 ].
The egg drop syndrome (76) PCR kit |
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PCR-V044-96D | Bioingentech | 100T | EUR 686.4 |
Egg Drop Syndrome One-Step PCR kit |
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Oneq-V026-100D | Bioingentech | 100T | EUR 1039.2 |
Egg Drop Syndrome One-Step PCR kit |
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Oneq-V026-150D | Bioingentech | 150T | EUR 1177.2 |
Egg Drop Syndrome One-Step PCR kit |
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Oneq-V026-50D | Bioingentech | 50T | EUR 861.6 |
The egg drop syndrome (76) RT PCR kit |
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RTq-V044-100D | Bioingentech | 100T | EUR 860.4 |
The egg drop syndrome (76) RT PCR kit |
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RTq-V044-150D | Bioingentech | 150T | EUR 969.6 |
The egg drop syndrome (76) RT PCR kit |
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RTq-V044-50D | Bioingentech | 50T | EUR 717.6 |
The egg drop syndrome (76) One-Step PCR kit |
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Oneq-V044-100D | Bioingentech | 100T | EUR 1039.2 |
The egg drop syndrome (76) One-Step PCR kit |
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Oneq-V044-150D | Bioingentech | 150T | EUR 1177.2 |
The egg drop syndrome (76) One-Step PCR kit |
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Oneq-V044-50D | Bioingentech | 50T | EUR 861.6 |
PCR Mix |
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L5051100 | Biochain | 2.5 ml | EUR 67 |
PRICE DROP |
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110-012 | GeneOn | 4 x 1000 µl | EUR 159.6 |
PRICE DROP |
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110-012L | GeneOn | 5x 4 x 1000 µl | EUR 621.6 |
PRICE DROP |
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110-012XL | GeneOn | 10x 4 x 1000 µl | EUR 1126.8 |
Ready? PCR Mix |
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M1127-1000 | Biovision | each | EUR 614.4 |
Ready? PCR Mix |
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M1127-200 | Biovision | each | EUR 229.2 |
Rigor? PCR Mix |
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M1132-200 | Biovision | each | EUR 385.2 |
Breeze? PCR Mix |
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M1134-200 | Biovision | each | EUR 320.4 |
Distant? PCR Mix |
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M1136-200 | Biovision | each | EUR 352.8 |
Advance? PCR Mix |
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M1139-200 | Biovision | each | EUR 451.2 |
Fire Start? PCR Mix |
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M1141-200 | Biovision | each | EUR 451.2 |
Ready? PCR Mix-Dye |
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M1128-1000 | Biovision | each | EUR 614.4 |
Ready? PCR Mix-Dye |
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M1128-200 | Biovision | each | EUR 229.2 |
Image Ready? PCR Mix |
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M1129-200 | Biovision | each | EUR 352.8 |
Rigor? PCR Mix-Dye |
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M1133-200 | Biovision | each | EUR 385.2 |
Whole Blood PCR Mix |
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M1143-200 | Biovision | each | EUR 385.2 |
Robust Ready? PCR Mix |
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M1130-1000 | Biovision | each | EUR 738 |
Robust Ready? PCR Mix |
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M1130-200 | Biovision | each | EUR 255.6 |
Breeze? PCR Mix-Dye |
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M1135-200 | Biovision | each | EUR 320.4 |
Distant? PCR Mix-Dye |
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M1137-200 | Biovision | each | EUR 352.8 |
Image Distant? PCR Mix |
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M1138-200 | Biovision | each | EUR 385.2 |
Advance? PCR Mix-Dye |
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M1140-200 | Biovision | each | EUR 451.2 |
PCR-EZ D-PCR MASTER MIX |
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BS294 | Bio Basic | 100RXN, 100prep | EUR 112.2 |
amfiSure PCR Master Mix |
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P0311-010 | GenDepot | 2x50 rxns | EUR 151.2 |
amfiSure PCR Master Mix |
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P0311-025 | GenDepot | 5X50 rxns | EUR 198 |
amfiSure PCR Master Mix |
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P0311-050 | GenDepot | 10X50 rxns | EUR 262.8 |
amfiSure PCR Master Mix |
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P0311-100 | GenDepot | 10x1ml | EUR 343.2 |
amfiSure PCR Master Mix |
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P0311-125 | GenDepot | 15X50 rxns | EUR 333.6 |
amfiSure PCR Master Mix |
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P0311-200 | GenDepot | 20x1ml | EUR 562.8 |
amfiSure PCR Master Mix |
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P0311-250 | GenDepot | 50x50 rxns | EUR 902.4 |
amfiSure PCR Master Mix |
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P0311-500 | GenDepot | 100x50 rxns | EUR 1509.6 |
amfiXpand PCR Master Mix |
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P0331-010 | GenDepot | 2X50 rxns | EUR 181.2 |
amfiXpand PCR Master Mix |
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P0331-025 | GenDepot | 5X50 rxns | EUR 327.6 |
amfiXpand PCR Master Mix |
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P0331-050 | GenDepot | 10X50 rxns | EUR 537.6 |
amfiXpand PCR Master Mix |
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P0331-250 | GenDepot | 50x50 rxns | EUR 2247.6 |
Taq 2x PCR Mix 100 rxn |
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BA01501 | Bioatlas | 100rxn | EUR 112.8 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
MyTaq Blood PCR Mix, 2x |
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BIO-25053/S | Bioline | Sample | Ask for price |
MyTaq Blood PCR Mix, 2x |
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BIO-25054 | Bioline | 250 Reactions | Ask for price |
HotTaq 2x PCR Mix 100 rxn |
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BA01503 | Bioatlas | 100rxn | EUR 144 |
Description: High quality HotTaq polymerase for different PCR variations and downstream applications. |
RedTaq 2x PCR Mix 100 rxn |
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BA01507 | Bioatlas | 100rxn | EUR 175.2 |
Description: High quality RedTaq polymerase for different PCR variations and downstream applications. |
Fire Start? PCR Mix-Dye |
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M1142-200 | Biovision | each | EUR 451.2 |
HiScript-TS 2 × PCR Mix |
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RA103-01 | Vazyme | 40 rxns (25 μl/rxn) | EUR 69.6 |
HiScript-TS 2 × PCR Mix |
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RA103-02 | Vazyme | 200 rxns (25 μl/rxn) | EUR 275.2 |
Funnel Pyrex Cyl Drop Gr.500ml |
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FUN4024 | Scientific Laboratory Supplies | EACH | EUR 176.4 |
Robust Ready? PCR Mix-Dye |
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M1131-1000 | Biovision | each | EUR 738 |
Robust Ready? PCR Mix-Dye |
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M1131-200 | Biovision | each | EUR 255.6 |
mRNAExpress Tail PCR mix (5uM) |
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MR-TAIL-PR | SBI | 100 ul | EUR 111 |
Drop Delay Calibration Particles |
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DDCP-70-2 | Spherotech | 2 mL | EUR 339.6 |
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
Drop Delay Calibration Particles |
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DDCP-70-20 | Spherotech | 20 mL | EUR 2301.6 |
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
Taq 5x PCR Mix 12.5 mM |
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BT10402 | Bioatlas | 250rxn | EUR 130.8 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
Drop Funnel Rotaflo SC 50ml |
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QD312 | Scientific Laboratory Supplies | PK5 | EUR 637.2 |
amfiSure Prime PCR Master Mix |
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P1311-025 | GenDepot | 5X50 rxns | EUR 193.2 |
amfiSure Prime PCR Master Mix |
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P1311-050 | GenDepot | 10X50 rxns | EUR 262.8 |
amfiSure Prime PCR Master Mix |
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P1311-125 | GenDepot | 15X50 rxns | EUR 327.6 |
amfiSure Prime PCR Master Mix |
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P1311-250 | GenDepot | 50x50 rxns | EUR 886.8 |
amfiSure Prime PCR Master Mix |
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P1311-500 | GenDepot | 100x50 rxns | EUR 1485.6 |
amfiSure Advanced PCR Master Mix |
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P2311-025 | GenDepot | 5X50 rxns | EUR 198 |
amfiSure Advanced PCR Master Mix |
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P2311-050 | GenDepot | 10X50 rxns | EUR 267.6 |
amfiSure Advanced PCR Master Mix |
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P2311-125 | GenDepot | 15X50 rxns | EUR 338.4 |
amfiSure Advanced PCR Master Mix |
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P2311-250 | GenDepot | 50x50 rxns | EUR 902.4 |
amfiSure Advanced PCR Master Mix |
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P2311-500 | GenDepot | 100x50 rxns | EUR 1534.8 |
Funnel Pyrex Cyl Drop Gr 1Ltr |
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FUN4026 | Scientific Laboratory Supplies | EACH | EUR 249.6 |
amfiSure ONE PCR Master Mix(2X) |
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P7000-005 | GenDepot | 5x1 ml | EUR 262.8 |
amfiSure ONE PCR Master Mix(2X) |
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P7000-010 | GenDepot | 10x1 ml | EUR 380.4 |
amfiSure ONE PCR Master Mix(2X) |
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P7000-050 | GenDepot | 50x1 ml | EUR 1453.2 |
amfiSure ONE PCR Master Mix(2X) |
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P7000-100 | GenDepot | 100x1 ml | EUR 2522.4 |
Drop Funnel Cyl Rota S/C 100ml |
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QD1/21GP | Scientific Laboratory Supplies | EACH | EUR 109.2 |
Drop Funnel Cyl Rota S/C 100ml |
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QD1/22GP | Scientific Laboratory Supplies | EACH | EUR 116.4 |
Drop Funnel Cyl Rota S/C 250ml |
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QD1/32GP | Scientific Laboratory Supplies | EACH | EUR 166.8 |
Drop Funnel Cylind Rota S/C 50ml |
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QD1/11GP | Scientific Laboratory Supplies | EACH | EUR 102 |
Watershed Hanging Drop Cover Slip Endstation |
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M-WS180320-24WCSES | MiTeGen | 1 UNIT | EUR 256 |
Description: Watershed Hanging Drop Cover Slip Endstation |
Taq PCR Master Mix (2X, Red Dye) |
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BS9297 | Bio Basic | 1ml | EUR 101.76 |
Taq PCR Master Mix (2X, Red Dye) |
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BS9298 | Bio Basic | 5ml | EUR 227.04 |
Taq PCR Master Mix (2X, Blue Dye) |
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BS9295 | Bio Basic | 1ml | EUR 101.76 |
Taq PCR Master Mix (2X, Blue Dye) |
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BS9296 | Bio Basic | 5ml | EUR 227.04 |
2×Taq PCR Master Mix(with dye) |
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K1034-1 | ApexBio | 1 ml | EUR 87.6 |
2×Taq PCR Master Mix(with dye) |
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K1034-100 | ApexBio | 100×1 ml | EUR 950.4 |
2×Taq PCR Master Mix(with dye) |
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K1034-20 | ApexBio | 20×1 ml | EUR 338.4 |
2×Taq PCR Master Mix(with dye) |
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K1034-5 | ApexBio | 5×1 ml | EUR 142.8 |
2×Taq PCR Master Mix(with dye) |
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K1034-50 | ApexBio | 50×1 ml | EUR 616.8 |
Drop Funnel P/Equal R S/C 100ml |
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QDE100/22 | Scientific Laboratory Supplies | EACH | EUR 192 |
HotStart PCR Master mix (2X, Green Dye) |
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BS9291 | Bio Basic | 5X1mL, 5ml | EUR 251.4 |
HotStart PCR Master mix (2X, Green Dye) |
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BS9292 | Bio Basic | 1ml | EUR 115.68 |
amfiSure Ultra Fidelity PCR Master Mix(2X) |
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P0346-001 | GenDepot | 1ml | EUR 336 |
amfiSure Ultra Fidelity PCR Master Mix(2X) |
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P0346-002 | GenDepot | 2x1ml | EUR 578.4 |
amfiSure Ultra Fidelity PCR Master Mix(2X) |
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P0346-005 | GenDepot | 5x1ml | EUR 993.6 |
amfiSure Ultra Fidelity PCR Master Mix(2X) |
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P0346-010 | GenDepot | 10x1ml | EUR 1632 |
amfiFusion High Fidelity PCR Master Mix(2X) |
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P0342-010 | GenDepot | 2x50 rxns | EUR 303.6 |
amfiFusion High Fidelity PCR Master Mix(2X) |
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P0342-025 | GenDepot | 5X50 rxns | EUR 546 |
amfiFusion High Fidelity PCR Master Mix(2X) |
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P0342-050 | GenDepot | 10X50 rxns | EUR 934.8 |
amfiFusion High Fidelity PCR Master Mix(2X) |
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P0342-100 | GenDepot | 20x50 rxns | EUR 1599.6 |
Reverse Transcriptase RT PCR Master Mix (5X) |
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MB1002-100reactions | BosterBio | 100 reactions | EUR 616.8 |
Reverse Transcriptase RT PCR Master Mix (5X) |
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MB1002-200reactions | BosterBio | 200 reactions | EUR 895.2 |
Reverse Transcriptase RT PCR Master Mix (5X) |
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MB1002-25reactions | BosterBio | 25 reactions | EUR 226.8 |
Extra T7 gRNA PCR primer mix (5 uM) |
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CAS510A-PR | SBI | 50 assays | EUR 99 |
Taq 5x PCR Mix Ready-to-Load 12.5 mM |
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BT10502 | Bioatlas | 250rxn | EUR 136.8 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
ReadiUseâ„¢ dNTP Mix Set *10 mM PCR Grade* |
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17258-1mL | AAT Bioquest | 1 mL | EUR 79 |
Description: 10 mM dNTP Mix is a mixture of four nucleotides (dATP, dCTP, dGTP, dTTP) in purified water. |
Original INTELLI-PLATE 96-2; 2-well sitting drop, 120 plates |
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MAR-102-0011-00 | MiTeGen | 120 PLATES | EUR 990 |
Description: Original INTELLI-PLATE 96-2; 2-well sitting drop, 120 plates |
2x Genotyping PCR Ready Master Mix (250 x 20µL rxn) |
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T403 | 101Bio | - | Ask for price |
INTELLI-PLATE 96-2 flat bottom; 2-well sitting drop, 120 plates |
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MAR-102-0001-01 | MiTeGen | 120 PLATES | EUR 990 |
Description: INTELLI-PLATE 96-2 flat bottom; 2-well sitting drop, 120 plates |
INTELLI-PLATE 96-2 low profile; 2-well sitting drop, 120 plates |
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MAR-102-0001-10 | MiTeGen | 120 PLATES | EUR 990 |
Description: INTELLI-PLATE 96-2 low profile; 2-well sitting drop, 120 plates |
INTELLI-PLATE 96-3 low profile; 3-well sitting drop, 120 plates |
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MAR-102-0001-13 | MiTeGen | 120 PLATES | EUR 990 |
Description: INTELLI-PLATE 96-3 low profile; 3-well sitting drop, 120 plates |
96 WELL SITTING DROP HIGH THROUGHPUT CRYSTALLOGRAPHY PLATE. |
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CP-AXYGEM-96-50 | CORNING | 10/pk | EUR 548.4 |
Description: Crystallography Plates; Crystallography Plates - Axygen |
INTELLI-PLATE 96-2 Shallow well; 2-well sitting drop, 120 plates |
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MAR-102-0001-20 | MiTeGen | 120 PLATES | EUR 990 |
Description: INTELLI-PLATE 96-2 Shallow well; 2-well sitting drop, 120 plates |
ReadiUse™ dNTP Mix Set *10 mM PCR Grade* |
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17258 | AAT Bioquest | 1 mL | EUR 79 |
24 Well, Hanging Drop Plate, Polystyrene, W/LID, 24/cs |
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M-662150 | MiTeGen | 24 PLATES | EUR 117 |
Description: 24 Well, Hanging Drop Plate, Polystyrene, W/LID, 24/cs |
INTELLI-PLATE 96-2 low vol. reservoir; 2-well sitting drop, 120 plates |
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MAR-102-0001-00 | MiTeGen | 120 PLATES | EUR 990 |
Description: INTELLI-PLATE 96-2 low vol. reservoir; 2-well sitting drop, 120 plates |
INTELLI-PLATE 96-3 low vol. reservoir; 3-well sitting drop, 120 plates |
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MAR-102-0001-03 | MiTeGen | 120 PLATES | EUR 990 |
Description: INTELLI-PLATE 96-3 low vol. reservoir; 3-well sitting drop, 120 plates |
Accuris High Fidelity PCR Master Mix, sample, 5 rxns |
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PR1001-HF-S | Benchmark Scientific | 1 each | EUR 7.1 |
Carbolite drop down door ELF 116B laboratory chamber furnace 6L |
|||
FUR1200 | Scientific Laboratory Supplies | EACH | EUR 2676 |
Carbolite drop down door ELF 114B laboratory chamber furnace 14L |
|||
FUR1202 | Scientific Laboratory Supplies | EACH | EUR 2881.2 |
INTELLI-PLATE 96-2 shallow well, low profile; 2-well sitting drop, 120 plates |
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MAR-102-0001-21 | MiTeGen | 120 PLATES | EUR 990 |
Description: INTELLI-PLATE 96-2 shallow well, low profile; 2-well sitting drop, 120 plates |
2x GoldStar Best PCR Master Mix (with Dyes), 20 ul/rxn |
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W0655-1 | 101Bio | - | Ask for price |
2x GoldStar Best PCR Master Mix (with Dyes), 20 ul/rxn |
|||
W0655-5 | 101Bio | - | Ask for price |
lyophilised real-time PCR Master Mix for dual labeled probes |
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M-PCR-156L | MiTeGen | 960 reactions x 20 µl | EUR 1023 |
Description: lyophilised real-time PCR Master Mix for dual labeled probes |
lyophilised real-time PCR Master Mix for dual labeled probes |
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M-PCR-156S | MiTeGen | 192 reactions x 20 µl | EUR 256 |
Description: lyophilised real-time PCR Master Mix for dual labeled probes |
amfiEco PCR Master Mix,8-Strip RTU(2X), for 50ul reaction |
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P0704-096 | GenDepot | 96 rxns | EUR 174 |
Aroclor Mix 1 |
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PCB-M1 | Scientific Laboratory Supplies | 1ML | EUR 31.2 |
Smart 2X PCR pre-mix Pfu (30ul) |
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9K-002-0038 | Bio Basic | 30uL, 30uL | EUR 697.37 |
Drop-n-Stain CF594 Goat anti-mouse IgG (H+L), highly corss-adsorbed |
|||
20957 | Biotium | 5mL | EUR 206.4 |
Description: Minimum order quantity: 1 unit of 5mL |
Drop-n-Stain CF543 Goat anti-mouse IgG (H+L), highly cross-adsorbed |
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20969 | Biotium | 5mL | EUR 206.4 |
Description: Minimum order quantity: 1 unit of 5mL |
Drop-n-Stain CF594 Goat anti-rabbit IgG (H+L), highly cross-adsorbed |
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20955 | Biotium | 5mL | EUR 206.4 |
Description: Minimum order quantity: 1 unit of 5mL |
Drop-n-Stain CF488A Goat anti-mouse IgG (H+L), highly cross-adsorbed |
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20956 | Biotium | 5mL | EUR 206.4 |
Description: Minimum order quantity: 1 unit of 5mL |
Furthermore, EIIA(Glc) was discovered to bind to the MalK dimer no matter its conformational state. Deletion of the amphipathic N-terminal peptide of EIIA(Glc), which is required for inhibition, diminished formation of cross-linked merchandise. Utilizing a spin-labeled transporter variant and EPR spectroscopy, we exhibit that EIIA(Glc) arrests the transport cycle by inhibiting the ATP-dependent closure of the MalK dimer.