Rv3634c from Mycobacterium tuberculosis H37Rv encodes an enzyme with UDP-Gal/Glc and UDP-GalNAc 4-epimerase activities.

Rv3634c from Mycobacterium tuberculosis H37Rv encodes an enzyme with UDP-Gal/Glc and UDP-GalNAc 4-epimerase activities.

A bioinformatics research revealed that Mycobacterium tuberculosis H37Rv (Mtb) incorporates sequence homologs of Campylobacter jejuni protein glycosylation enzymes. The ORF Rv3634c from Mtb was recognized as a sequence homolog of C. jejuni UDP-Gal/GalNAc 4-epimerase. This research reviews the cloning of Rv3634c and its expression as an N-terminal His-tagged protein. The recombinant protein was proven to have UDP-Gal/Glc 4-epimerase exercise by GOD-POD assay and by reverse section HPLC. This enzyme was proven to have UDP-GalNAc 4-epimerase exercise additionally. Residues Ser121, Tyr146 and Lys150 have been proven by site-directed mutagenesis to be vital for enzyme exercise.

Mutation of Ser121 and Tyr146 to Ala and Phe, respectively, led to finish lack of exercise whereas mutation of Lys150 to Arg led to partial lack of exercise. There have been no gross modifications within the secondary constructions of any of those three mutants. These outcomes counsel that Ser121 and Tyr146 are important for epimerase exercise of Rv3634c. UDP-Gal/Glc 4-epimerases from different organisms even have a catalytic triad consisting of Ser, Tyr and Lys.

The triad carries out proton switch from nucleotide sugar to NAD+ and again, thus effecting the epimerization of the substrate. Addition of NAD+ to Lys150 considerably abrogates the lack of exercise, suggesting that, as in different epimerases, NAD+ is related to Rv3634c. Right here, we present that EIIA(Glc) of the glucose-specific PTS system can be required for the traditional decay of those sRNAs and that it acts by binding to the EAL area of CsrD. Solely the unphosphorylated type of EIIA(Glc) sure to CsrD in vitro and was able to activating CsrB/C turnover in vivo.

Csr is a conserved international regulatory system, which makes use of the sequence-specific RNA-binding protein CsrA to activate or repress gene expression by binding to mRNA and altering translation, stability and/or transcript elongation. In Escherichia coli, CsrA exercise is regulated by two sRNAs, CsrB and CsrC, which bind to a number of CsrA dimers, thereby sequestering this protein away from its mRNA targets. Turnover of CsrB/C sRNAs is tightly regulated by a GGDEF-EAL area protein, CsrD, which targets them for cleavage by RNase E.

The conundrum of UDP-Glc entrance into the yeast ER lumen.

UDP-Glc entrance into the endoplasmic reticulum (ER) of eukaryotic cells is a key step within the high quality management of glycoprotein folding, a mechanism requiring switch of a Glc residue from the nucleotide sugar (NS) to glycoprotein folding intermediates by the UDP-Glc:glycoprotein glucosyltransferase (UGGT). In keeping with a bioinformatics search there are solely eight genes within the Schizosaccharomyces pombe genome belonging to the three Pfam households to which all recognized nucleotide-sugar transporters (NSTs) of the secretory pathway belong.

The protein merchandise of two of them (hut1+ and yea4+) localize to the ER, these of genes gms1+, vrg4+, pet1+, pet2+ and pet3+ to the Golgi, whereas that of gms2+ has an unknown location. Right here we show that (1) Δhut1 and Δgpt1 (UGGT null) mutants share a number of phenotypic options; (2) Δhut1 mutants present a 50% discount in UDP-Glc transport into ER-derived membranes; (3) in vivo UDP-Glc ER entrance occurred in Δhut1Δyea4Δgms2 mutants and in cells through which Δhut1 disruption was mixed with that of every of 4 of the genes encoding Golgi-located proteins.

Rv3634c from Mycobacterium tuberculosis H37Rv encodes an enzyme with UDP-Gal/Glc and UDP-GalNAc 4-epimerase activities.

Subsequently, disruption of all genes whose merchandise localize to the ER or have an unknown location didn’t obliterate UDP-Glc ER entrance. We conclude that the hut1+ gene product is concerned in UDP-Glc entrance into the ER, however that a minimum of one other as but unknown NST displaying an unconventional sequence operates within the yeast secretory pathway. This conclusion agrees with our earlier outcomes exhibiting that UDP-Glc entrance into the yeast ER doesn’t observe the classical NST antiport mechanism.

The research on the preparation and characterization of gene-loaded immunomagnetic albumin nanospheres and their anti-cell proliferative impact mixed with magnetic fluid hyperthermia on GLC-82 cells.

As one of the vital frequent malignant tumors, the medical and socio-economic penalties of lung most cancers are important. At the moment, surgical procedure is the primary therapy technique for this illness, however the survival charges of lung most cancers sufferers are usually not ultimate as a result of excessive recurrence fee of the illness. Subsequently, many researchers are exploring new particular therapeutic strategies which might be extremely healing and minimally cytotoxic to wholesome tissues. To this finish, albumin nanospheres concurrently have been loaded with super-paramagnetic iron oxide nanoparticles (as gene vector and anticancer gene), and plasmid pDONR223-IFNG, and modified with anti-EGFR monoclonal antibody cetuximab as remedy.

Focusing on brokers, specifically gene-loaded immunomagnetic albumin nanospheres (cetuximab [C225]-IFNG-IMANS), have been ready for focused lung carcinoma cells (GLC-82 cell strains). Transmission electron microscopy photographs confirmed that the C225-IFNG-IMANS have been efficiently ready, and the power of the nanospheres to focus on GLC-82 cells in vitro was confirmed by Prussian blue staining, immunofluorescence experiments, and magnetic resonance imaging. Transfection images and agarose gel electrophoresis proved that pDONR223-IFNG might be encased within the albumin nanospheres.

A Cell Counting Equipment-Eight assay confirmed that the mixture remedy group had considerably extra therapeutic results on GLC-82 cells than different remedy teams. A stream cytometry assay confirmed that the apoptotic index of the mixed therapy group was 67.68%, whereas the indices of the C225 group, gene remedy group, and magnetic fluid hyperthermia group have been 12.2%, 16.34%, and 20.04% respectively.

Methylamp Universal Methylated DNA Preparation Kit

P-1019 40 µg
EUR 347.25
Description: The best epigenetics products

100 BP DNA LADDER, 500UL PER KIT

M-DNA-100BP 1/pk
EUR 73
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT

M-DNA-1KB 1/pk
EUR 70
Description: Bioscience Mol Bio; DNA Ladder

VAHTS Universal DNA Library Prep Kit for MGI

NDM607-01 24 rxn
EUR 733

VAHTS Universal DNA Library Prep Kit for MGI

NDM607-02 96 rxn
EUR 2136

2K DNA Marker

20-abx098045
  • EUR 258.00
  • EUR 189.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

5K DNA Marker

20-abx098048
  • EUR 258.00
  • EUR 189.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

15K DNA Marker

20-abx098049
  • EUR 272.00
  • EUR 189.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

1Kb DNA Marker

20-abx098050
  • EUR 258.00
  • EUR 189.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

100bp DNA Marker

20-abx098052
  • EUR 272.00
  • EUR 189.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

100bp DNA Marker

D1100-050 50㎍
EUR 165

100bp DNA Marker

D1100-250 5X50㎍
EUR 550

1Kb DNA Marker

D1101-050 50㎍
EUR 131

1Kb DNA Marker

D1101-250 5X50㎍
EUR 300

DL5000 DNA Marker

MD102-01 250 μl
EUR 107

DL5000 DNA Marker

MD102-02 500 μl
EUR 113

DL15000 DNA Marker

MD103-01 250 μl
EUR 109

DL15000 DNA Marker

MD103-02 500 μl
EUR 115

VAHTS Universal DNA Library Prep Kit for Illumina V3

ND607-01 24 rxn
EUR 441

VAHTS Universal DNA Library Prep Kit for Illumina V3

ND607-02 96 rxn
EUR 1405

VAHTS Universal Pro DNA Library Prep Kit for Illumina

ND608-01 24 rxn
EUR 465

VAHTS Universal Pro DNA Library Prep Kit for Illumina

ND608-02 96 rxn
EUR 1549

VAHTS Universal Plus DNA Library Prep Kit for Illumina

ND617-01 24 rxn
EUR 492

VAHTS Universal Plus DNA Library Prep Kit for Illumina

ND617-02 96 rxn
EUR 1605

VAHTS Universal DNA Library Prep Kit for Ion Torrent

ND701-01 24 rxn
EUR 733

VAHTS Universal DNA Library Prep Kit for Ion Torrent

ND701-02 96 rxn
EUR 2136

VAHTS Universal Pro DNA Library Prep Kit for MGI

NDM608-01 24 rxn
EUR 756

VAHTS Universal Pro DNA Library Prep Kit for MGI

NDM608-02 96 rxn
EUR 2284

VAHTS Universal Plus DNA Library Prep Kit for MGI

NDM617-01 24 rxn
EUR 824

VAHTS Universal Plus DNA Library Prep Kit for MGI

NDM617-02 96 rxn
EUR 2408

UNIVERSAL PLATFORM

480144 1/pk
EUR 269
Description: Lab Equipment; Constant Temperature Equipment

1Kb Plus DNA Marker

20-abx098051
  • EUR 300.00
  • EUR 203.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

DL2000 Plus DNA Marker

MD101-01 250 μl
EUR 107

DL2000 Plus DNA Marker

MD101-02 500 μl
EUR 113

Linear Kinetoplast DNA Marker

TG2018-1 10 ug
EUR 179

Decatenated Kinetoplast DNA Marker

TG2020-1 10 ug
EUR 190

Relaxed pRYG DNA Marker

TG2025-1 10 ug
EUR 268

Linear pRYG DNA Marker

TG2028-1 10 ug
EUR 179

1 Kb Ladder DNA Marker

FYD001-500UL 20 µg/ 500 µl Ask for price

100 bp Ladder DNA Marker

FYD002-500UL 30 µg/ 500 µl Ask for price

50 bp Ladder DNA Marker

FYD004-500UL 32.5 µg/ 500 µl Ask for price

Universal Detachment Solution

AD002 100 ml
EUR 148

Universal Spring Platform

H1000-P-SP 1 PC
EUR 323.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Universal Coating Solution

AC002 20 ml
EUR 297

Universal Neutralization Buffer

NB001 100 ml
EUR 135

UNIVERSAL BEER AGAR

U21-100-10kg 10 kg
EUR 1524

UNIVERSAL BEER AGAR

U21-100-2kg 2kg
EUR 370

UNIVERSAL BEER AGAR

U21-100-500g 500 g
EUR 137

UNIVERSAL PREENRICHMENT BROTH

U21-101-10kg 10 kg
EUR 749

UNIVERSAL PREENRICHMENT BROTH

U21-101-2Kg 2 Kg
EUR 202

UNIVERSAL PREENRICHMENT BROTH

U21-101-500g 500 g
EUR 91

Universal qPCR Mixture

QPCR1000-UNIV 4X1.25ml
EUR 276.2
  • Product category: PCR Related/PCR Premix (qPCR)/qPCR Premix + Taq

VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free)

ND607-03 24 rxn
EUR 429

VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free)

ND607-04 96 rxn
EUR 1354

Image Green? 100 bp DNA Marker

M1155-500
EUR 294

Image Green? 1 kb DNA Marker

M1156-500
EUR 294

50-500bp Low Range DNA Marker

GM305 200loading, 200prep
EUR 114.82
  • Product category: Electrophoresis Related/Ladders - DNA/50-500 bp

500-10000bp DNA Marker, Original Form

M101O-1 100loading, 100prep
EUR 91.76
  • Product category: Electrophoresis Related/Ladders - DNA/500-10000 bp

500-10000bp DNA Marker, Original Form

M101O-2 5x100loading, 500prep
EUR 219.65
  • Product category: Electrophoresis Related/Ladders - DNA/500-10000 bp

100-1500bp DNA Marker, Original Form

M102O-1 100loading, 100prep
EUR 90.02
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Original Form

M102O-2 5x100loading, 500prep
EUR 215.3
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Original Form

M107O-1 100loading, 100prep
EUR 91.76
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Original Form

M107O-2 5x100loading, 500prep
EUR 219.65
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

2K Plus DNA Marker (8 linear double-stranded DNA bands)

20-abx098046
  • EUR 258.00
  • EUR 189.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

2K Plus DNA Marker (9 linear double-stranded DNA bands)

20-abx098047
  • EUR 258.00
  • EUR 189.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

100bp Plus DNA Marker (12 linear double-stranded DNA bands)

20-abx098053
  • EUR 272.00
  • EUR 189.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

100bp Plus DNA Marker (14 linear double-stranded DNA bands)

20-abx098054
  • EUR 300.00
  • EUR 203.00
  • 2.5 ml
  • 500 ul
  • Shipped within 5-10 working days.

5min Universal Ligation Mix

C311-01 50 rxn
EUR 214

5min Universal Ligation Mix

C311-02 100 rxn
EUR 283

Universal Casein Diluent/Blocker

85R-108 250 ml
EUR 230
Description: Ready-to-use biotin free reagent applicable for blocking ELISA plates

PCR plate-foil universal

A28216 1x100 pcs
EUR 94

PCR plate-foil universal

A28216L 5x100 pcs
EUR 310

Universal Full Growth Medium

TM001 500 ml
EUR 336

Universal Protein Precipitating Reagent

BSP012 100preps
EUR 81.32
  • Product category: Molecular Biology Kits/Protein - Purification/Precipitation

Tumour Marker MUC1 (S1.1) , DNA Aptamer, Biotinylated

AD-152-B Custom Ask for price

Tumour Marker MUC1 (S1.1) , DNA Aptamer, unlabeled

AD-152-U Custom Ask for price

100-1200bp DNA Marker, Ready-to-use

GM333 50loading, 50prep
EUR 67.4
  • Product category: Electrophoresis Related/Ladders - DNA/100-1200 bp

100-1200bp DNA Marker, Ready-to-use

GM334 5x50loading, 250prep
EUR 128.3
  • Product category: Electrophoresis Related/Ladders - DNA/100-1200 bp

100-2000bp DNA Marker, Ready-to-use

GM335 50loading, 50prep
EUR 67.4
  • Product category: Electrophoresis Related/Ladders - DNA/100-2000 bp

100-2000bp DNA Marker, Ready-to-use

GM336 5x50loading, 250prep
EUR 128.3
  • Product category: Electrophoresis Related/Ladders - DNA/100-2000 bp

200-1500bp DNA Marker, Ready-to-use

GM337 50loading, 50prep
EUR 67.4
  • Product category: Electrophoresis Related/Ladders - DNA/200-1500 bp

200-1500bp DNA Marker, Ready-to-use

GM338 5x50loading, 250prep
EUR 128.3
  • Product category: Electrophoresis Related/Ladders - DNA/200-1500 bp

200-2000bp DNA Marker, Ready-to-use

GM339 50loading, 50prep
EUR 67.4
  • Product category: Electrophoresis Related/Ladders - DNA/200-2000 bp

200-2000bp DNA Marker, Ready-to-use

GM340 5x50loading, 250prep
EUR 128.3
  • Product category: Electrophoresis Related/Ladders - DNA/200-2000 bp

300-2500bp DNA Marker, Ready-to-use

GM341 50loading, 50prep
EUR 67.4
  • Product category: Electrophoresis Related/Ladders - DNA/300-2500 bp

300-2500bp DNA Marker, Ready-to-use

GM342 5x50loading, 250prep
EUR 128.3
  • Product category: Electrophoresis Related/Ladders - DNA/300-2500 bp

100-1000bp DNA Marker, Ready-to-use

GM343 50loading, 50prep
EUR 80.45
  • Product category: Electrophoresis Related/Ladders - DNA/100-1000 bp

100-1000bp DNA Marker, Ready-to-use

GM345 50loading, 50prep
EUR 84.8
  • Product category: Electrophoresis Related/Ladders - DNA/100-1000 bp

500-10000bp DNA Marker, Ready-to-use

M101R-1 100loading, 100prep
EUR 91.76
  • Product category: Electrophoresis Related/Ladders - DNA/500-10000 bp

500-10000bp DNA Marker, Ready-to-use

M101R-2 5x100loading, 500prep
EUR 219.65
  • Product category: Electrophoresis Related/Ladders - DNA/500-10000 bp

100-1500bp DNA Marker, Ready-to-use

M102R-1 100loading, 100prep
EUR 90.02
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Ready-to-use

M102R-2 5x100loading, 500prep
EUR 215.3
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

Lambda DNA/HindIII Marker, Ready-to-use

M104R-1 100loading, 100prep
EUR 65.66
  • Product category: Electrophoresis Related/Ladders - DNA/Lambda DNA/HindIII

Lambda DNA/HindIII Marker, Ready-to-use

M104R-2 5x100loading, 500prep
EUR 124.82
  • Product category: Electrophoresis Related/Ladders - DNA/Lambda DNA/HindIII

100-1500bp DNA Marker, Ready-to-use

M107R-1 100loading, 100prep
EUR 91.76
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Ready-to-use

M107R-2 5x100loading, 500prep
EUR 219.65
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

50-1500bp DNA Marker, Ready-to-use

M109-A 100loading, 100prep
EUR 91.76
  • Product category: Electrophoresis Related/Ladders - DNA/50-1500 bp

50-1500bp DNA Marker, Ready-to-use

M109-B 5x100loading, 500prep
EUR 219.65
  • Product category: Electrophoresis Related/Ladders - DNA/50-1500 bp

100-1500bp DNA Marker, Ready-to-use

SGM01 50loading, 50prep
EUR 67.4
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Ready-to-use

SGM02 5x50loading, 250prep
EUR 128.3
  • Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

UNIVERSAL LINEAR 4 PLACE STAND

AP-USD4 1/pk
EUR 70
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

HotTaq Probe qPCR Universal Mix

BT11004 250rxn
EUR 123
Description: High quality HotTaq polymerase for different PCR variations and downstream applications.

HotTaq EvaGreen qPCR Universal Mix

BT11104 250rxn
EUR 138
Description: High quality HotTaq polymerase for different PCR variations and downstream applications.

Universal IHC Diluent/Blocker/Stabilizer

85R-1021 1 liter
EUR 692
Description: Universal Diluent/Blocker/Stabilizer for use in IHC

VAHTS Universal Plus Fragmentation Module

N209-01 24 rxn
EUR 376

VAHTS Universal Plus Fragmentation Module

N209-02 96 rxn
EUR 1022

Universal 3' miRNA Reverse Primer

MPH00000 150 ul / 10 uM
EUR 70

100UL UNIVERSAL FIT FILTER TIPS

TF-100 1000/pk
EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

1000UL UNIVERSAL FIT FILTER TIPS

TF-1000 1000/pk
EUR 232
Description: Filter Tip; Filter Tips Pipette - Axygen

200UL UNIVERSAL FIT FILTER TIPS

TF-200 1000/pk
EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

300UL UNIVERSAL FIT FILTER TIPS

TF-350 1000/pk
EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

50UL UNIVERSAL FIT FILTER TIPS

TF-50 1000/pk
EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

Tumour Marker MUC1 (S1.1) , DNA Aptamer, FITC labeled

AD-152-F Custom Ask for price

100bp DNA Marker Plus-50, Ready-to-use

D1103-050 500 ul
EUR 151

100bp DNA Marker Plus-50, Ready-to-use

D1103-100 2x500 ul
EUR 192

100bp PCR Ranger DNA Marker, 100bp-To-3Kb

D1108-100 1ml
EUR 220

100bp PCR Ranger DNA Marker, 100bp-To-3Kb

D1108-200 2x1ml
EUR 309

1Kb PCR Ranger DNA Marker, 750bp-To-20Kb

D1109-100 1ml
EUR 188

1Kb PCR Ranger DNA Marker, 750bp-To-20Kb

D1109-400 4x1ml
EUR 388

200-2000bp DNA Marker Plus, Ready-to-use

GM401 50loading, 50prep
EUR 60.44
  • Product category: Electrophoresis Related/Ladders - DNA/200-2000 bp

100-5000bp DNA Marker Plus, Ready-to-use

SGM03 50loading, 50prep
EUR 67.4
  • Product category: Electrophoresis Related/Ladders - DNA/100-5000 bp

UNIVERSAL STAND FOR FOUR PIPETTORS, RED

AP-USD4-P 1/pk
EUR 69
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

UNIVERSAL STAND FOR SIX PIPETTORS, TRANSPARENT

AP-USD6 1/pk
EUR 85
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Human Adult Tissues Protein lysate, Universal

HUUL-4565 1 mg
EUR 524

Universal miRNA qPCR Primer (10 µM)

abx298006-200ul 200 ul
EUR 189
  • Shipped within 5-10 working days.

Universal Stress Protein F (uspF) Antibody

20-abx300670
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Enhanced Universal IHC Diluent/Blocker/Stabilizer

85R-1021E 100 ml
EUR 187
Description: Enhanced Universal Diluent/Blocker/Stabilizer for use in IHC

Universal TT epitope P2 (830-844)

5-02048 4 x 1mg Ask for price

UNIVERSAL CAROUSEL RACK FOR SIX PIPETTES

4078 1/pk
EUR 132
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

UNIVERSAL LINEAR RACK FOR SIX PIPETTES

4079 1/pk
EUR 70
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

STAT Universal Animal IHC KIT-small

329ANK-20 Small Kit
EUR 717

STAT Universal Animal IHC KIT-large

329ANK-60 Large Kit
EUR 1088

ADPsensor? Universal Kinase Activity Assay Kit

K212-100
EUR 582

Dog Adult Tissues Protein lysate, Universal

DOUL-4568 1 mg
EUR 524

Chicken Adult Tissues Protein lysate, Universal

CHUL-4567 1 mg
EUR 524

UNIVERSAL POWER SUPPLY FOR AXYGEN MOTOPET

MOTO-SP-PWR 1/pk
EUR 61
Description: Handheld Pipettor Repairs; Liquid Handling Device Repairs

Mouse Adult Tissues Protein lysate, Universal

MOUL-4566 1 mg
EUR 524

Monkey Adult Tissues Protein lysate, Universal

MKUL-4569 1 mg
EUR 524

Universal Protein Lysate: Human Normal Tissues

P4234565 4x0.5 mg
EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Human Normal Tissues

P4234565-1 2x0.5 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Mouse Normal Tissues

P4334566 4x0.5 mg
EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Mouse Normal Tissues

P4334566-1 2x0.5 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Rat Normal Tissues

P4434567 4x0.5 mg
EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Rat Normal Tissues

P4434567-1 2x0.5 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Monkey Normal Tissues

P4534565 4x0.5 mg
EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Monkey Normal Tissues

P4534565-1 2x0.5 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Dog Normal Tissues

P4734565 4x0.5 mg
EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Dog Normal Tissues

P4734565-1 2x0.5 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Chicken Normal Tissues

P4C34565 4x0.5 mg
EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Chicken Normal Tissues

P4C34565-1 2x0.5 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Rat Adult Tissues Protein lysate, Universal

RTUL-4570 1 mg
EUR 524

AceQ Universal SYBR qPCR Master Mix

Q511-02 500 rxn (20 μl/rxn)
EUR 221

AceQ Universal SYBR qPCR Master Mix

Q511-03 2500 rxn (20 μl/rxn)
EUR 646

ChamQ Universal SYBR qPCR Master Mix

Q711-02 500 rxn (20 μl/rxn)
EUR 221

ChamQ Universal SYBR qPCR Master Mix

Q711-03 2500 rxn (20 μl/rxn)
EUR 646

Universal RNA from Human Normal Tissues

R4234565 4x100 ug
EUR 628
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Human Normal Tissues

R4234565-1 2x100 ug
EUR 390
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Mouse Normal Tissues

R4334566 4x100 ug
EUR 530
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Mouse Normal Tissues

R4334566-1 2x100 ug
EUR 311
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Rat Normal Tissues

R4434567 4x100 ug
EUR 530
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Rat Normal Tissues

R4434567-1 2x100 ug
EUR 311
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Monkey Normal Tissues

R4534565 4x100 ug
EUR 628
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Monkey Normal Tissues

R4534565-1 2x100 ug
EUR 390
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Dog Normal Tissues

R4734565 4x100 ug
EUR 628
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Dog Normal Tissues

R4734565-1 2x100 ug
EUR 390
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Chicken Normal Tissues

R4C34565 4x100 ug
EUR 628
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Chicken Normal Tissues

R4C34565-1 2x100 ug
EUR 390
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

pSMPUW Universal Lentiviral Expression Vector (Promoterless)

VPK-211 10 µg
EUR 624
Description: Clone your gene of interest and a gene-specific promoter into this Lentiviral Expression Vector, then co-transfect along with lentiviral packaging vectors into a packaging cell line such as 293T or 293LTV. This expression vector is compatible with any 2nd or 3rd generation lentiviral packaging system, but due to its design it is best matched with our ViraSafe packaging vectors to produce the highest viral titer.

ViraSafe Universal Lentiviral Expression System, Ecotropic

VPK-211-ECO 1 kit
EUR 1163
Description: Lentivirus based on HIV-1 provides a powerful means for gene expression because it can infect both dividing and non-dividing cells. Other 3rd generation lentiviral packaging systems provide a reduced risk of replication-competent virus, but a small risk remains. Our ViraSafe Lentivirus Expression Complete Systems provide a safer method even compared to other 3rd generation expression systems. Overlap with native HIV genes has been reduced much further, thereby substantially reducing the chance of generating replication-competent virus. The system has been engineered so that lentiviral titers remain at the levels of third generation systems. Our Ecotropic Expression Systems assemble lentiviruses with an ecotropic envelope protein which will readily infect only mouse and rat cells via receptor-mediated binding, providing an additional level of safety. However, ecotropic viruses are not as stable upon freezing and will not survive ultracentrifugation procedures.

ViraSafe Universal Lentiviral Expression System, Pantropic

VPK-211-PAN 1 kit
EUR 1163
Description: Lentivirus based on HIV-1 provides a powerful means for gene expression because it can infect both dividing and non-dividing cells. Other 3rd generation lentiviral packaging systems provide a reduced risk of replication-competent virus, but a small risk remains. Our ViraSafe Lentivirus Expression Complete Systems provide a safer method even compared to other 3rd generation expression systems. Overlap with native HIV genes has been reduced much further, thereby substantially reducing the chance of generating replication-competent virus. The system has been engineered so that lentiviral titers remain at the levels of third generation systems. The Pantropic Expression Systems assemble VSVG-pseudotyped lentiviruses which can easily infect virtually any cells regardless of their species of origin.

RAPAd® Universal Adenoviral Expression System

VPK-250 1 kit
EUR 1036
Description: Making an adenovirus with traditional recombinant methods takes 2-3 months and requires tedious plaque recombination. More recent technologies have shortened this time somewhat, but still produce relatively high amounts of wild type (replication-competent) plaques, levels of which increase with serial amplification. The RAPAd® Adenoviral Expression Systems produce recombinant adenovirus with substantially reduced wild-type virus, while considerably shortening the production time to 2-3 weeks. Serial amplification of adenovirus produced using the RAPAd® system does not significantly increase replication-competent adenovirus levels. The system uses a backbone vector from which the 5' ITR, packaging signal and E1 sequences have been removed. The RAPAd® Universal Adenoviral Expression System (# VPK-250) contains a promoterless shuttle vector to allow you to insert the promoter of your choice along with your gene of interest to maximize gene expression.

100bp PCR Ranger DNA Marker, 100bp-To-3Kb, Concentrated

D2108-500 10x50ug
EUR 901

1.5 kb to 48.5 kb High Range DNA Marker

E255 150ug, 150ug
EUR 315.35
  • Product category: Electrophoresis Related/Ladders - DNA/1.5-48.5 kb

Universal Stress Protein F (USPF) Antibody (HRP)

20-abx300671
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Universal Stress Protein F (USPF) Antibody (FITC)

20-abx300672
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Universal Stress Protein F (USPF) Antibody (Biotin)

20-abx300673
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

EZBlock? Universal Protease and Phosphatase Inhibitor Cocktail

K283-1
EUR 218

EZBlock? Universal Protease and Phosphatase Inhibitor Cocktail

K283-set
EUR 620

Salmonella typhi Universal stress protein A (uspA)

1-CSB-YP820596SWW
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 17.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Salmonella typhi Universal stress protein A(uspA) expressed in Yeast

Salmonella typhi Universal stress protein A (uspA)

1-CSB-MP820596SWW
  • EUR 319.00
  • EUR 1081.00
  • EUR 451.00
  • EUR 801.00
  • 100ug
  • 1MG
  • 200ug
  • 500ug
  • MW: 19.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Salmonella typhi Universal stress protein A(uspA) expressed in Mammalian cell

Salmonella typhi Universal stress protein A (uspA)

1-CSB-EP820596SWW
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 19.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Salmonella typhi Universal stress protein A(uspA) expressed in E.coli

Escherichia coli Universal stress protein F (uspF)

1-CSB-EP339887ENV
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 32 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Escherichia coli Universal stress protein F(uspF) expressed in E.coli

Escherichia coli Universal stress protein D (uspD)

1-CSB-EP364467ENV
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 20.4 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Escherichia coli Universal stress protein D(uspD) expressed in E.coli

miRNA Universal SYBR® qPCR Master Mix

MQ101-01 125 rxn(20 μl/rxn)
EUR 138

miRNA Universal SYBR® qPCR Master Mix

MQ101-02 500 rxn(20 μl/rxn)
EUR 242

VAHTS Universal End preparation Module for Illumina

N203-01 24 rxn
EUR 243

VAHTS Universal End preparation Module for Illumina

N203-02 96 rxn
EUR 560

VAHTS Universal Adapter Ligation Module for Illumina

N204-01 24 rxn
EUR 329

VAHTS Universal Adapter Ligation Module for Illumina

N204-02 96 rxn
EUR 831

QuantiMir 3'-Universal Primer (10,000 qPCR reactions)

RA420AU-3 10,000 assays
EUR 178
  • Category: MicroRNA Tools

SeraMir 3'-Universal Primer (10,000 qPCR reactions)

RA800P-3 10,000 reactions
EUR 178
  • Category: MicroRNA Tools

AceQ U+ Universal Probe Master Mix V2

Q513-02 500 rxn (20 μl/rxn)
EUR 267

AceQ U+ Universal Probe Master Mix V2

Q513-03 2500 rxn (20 μl/rxn)
EUR 842

200UL CLEAR UNIVERSAL FIT STERILIZED PIPET TIPS

T-200-C-STK-S 480/pk
EUR 144
Description: Non Filter Tips; Pipette Tips - Axygen

150UL STERILIZED UNIVERSAL FIT FILTERED PIPET TIPS

TF-150-R-S 960/pk
EUR 268
Description: Filter Tip; Filter Tips Pipette - Axygen

200UL "MAXYMUM RECOVERY" UNIVERSAL FIT REFERENCE TIPS

TR-222-C-L 1000/pk
EUR 248
Description: Non Filter Tips; Maxymum Recovery Pipette Tips - Axygen

ACTGene? DNA Marker, 1 kb Ladder, 13 Fragments, 100 loads

ACT-IDMWD1
EUR 149

ACTGene? DNA Marker, 100 bp Ladder, 11 Fragments, 100 loads

ACT-IDMWD100
EUR 149

Double Stranded DNA (dsDNA) (Nuclear Marker); Clone 121-3 (Concentrate)

RA0417-C.1 0.1 ml
EUR 125

Double Stranded DNA (dsDNA) (Nuclear Marker); Clone 121-3 (Concentrate)

RA0417-C.5 0.5 ml
EUR 300

Subsequently, the mixture of thermal therapy, molecular focused therapy, and gene therapy synergistically targets GLC-82 cells, and the usage of C225-IFNG-IMANS as a gene or drug provider provides a novel and promising strategy for the therapy of lung most cancers.

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