Glycoproteins are sometimes acknowledged as not-self molecules by antibodies triggering the onset of extreme autoimmune illnesses resembling A number of Sclerosis (MS). Thus, the event of antigen-mimicking biomarkers represents a sexy technique for an early analysis of the illness. An instance is the artificial glycopeptide CSF114(Glc), which was designed and examined as MS biomarker and whose scientific utility was restricted by its diminished capability to detect autoantibodies in MS sufferers. Within the try to enhance the efficacy of CSF114(Glc), we’ve characterised all of the occasions resulting in the ultimate binding of the biomarker to the autoantibody utilizing atomistic simulations, ESR and NMR experiments. The glycosydic moiety performs a major function in the entire course of.

Particularly, in an setting mimicking that used within the scientific checks the glycopeptide assumes a α-helix construction that’s useful for the interplay with the antibody. On this conformation CSF114(Glc) binds the monoclonal antibody mAb8-18C5 equally to the myelin oligodendrocyte glycoprotein MOG, which is a identified MS auto-antigen, thus explaining its diagnostic exercise. Our examine provides new molecular bases to design more practical biomarkers and offers a most legitimate protocol to analyze different methods the place the setting impact is determinant for the organic exercise.

The current examine was carried out to look at the dissipation sample of triazophos on capsicum and danger evaluation of its residues on human beings and to recommend a ready interval for the protection of customers. Following two functions of triazophos (Truzo 40 EC) at 500 and 1000 g a.i. ha(-1), the typical preliminary deposits had been discovered to be 3.61 and 6.26 mg kg(-1), respectively. These residues dissipated beneath the restrict of quantification (LOQ) of 0.05 mg kg(-1) in 10 and 15 days on the beneficial and double the beneficial dosages, respectively. The calculated values of half-life had been 2.31 and a couple of.

14 days at beneficial and double the beneficial dosages, respectively. Theoretical most residue contribution (TMRC) values had been discovered to be 28.eight and 41.6 μg individual(-1) day(-1) at 500 and 1000 g a.i. ha(-1), respectively, and located to be beneath the utmost permissible consumption on capsicum fruit on the seventh day. Subsequently, a ready interval of seven days is recommended for consumption of capsicum sprayed with triazophos on the beneficial dosages.

Preliminary examine on utility of urine amino acids profiling for monitoring of renal tubular damage utilizing GLC-MS.

A easy methodology for isolation and purification of DIBOA-Glc from Tripsacum dactyloides.

Naturally occurring benzoxazinones (Bx) are a extremely reactive class of compounds which have obtained specific consideration prior to now a number of many years. Lately, we recognized 2-β-D-glucopyranosyloxy-4-hydroxy-1,4-benzoxazin-3-one (DIBOA-Glc) because the compound current within the roots of Japanese gamagrass {Tripsacum dactyloides (L.)} accountable for atrazine degradation. Nonetheless, characterization of the DIBOA-Glc/atrazine degradation response has been restricted on account of difficulties achieve ample portions of purified DIBOA-Glc.

The target of the examine was to develop a easy purification and isolation methodology for acquiring bulk portions of extremely purified DIBOA-Glc. T. dactyloides roots had been extracted with 90% aqueous methanol, and the crude extract was fractionated utilizing an HPLC geared up with a C8 semi-prep column and fraction collector. UHPLC-DAD-MS/MS was used to verify the identification of DIBOA-Glc within the fractions collected. Evaluation by 13C and 1H NMR and DAD indicated that 542 mg of DIBOA-Glc with a purity of>> 99% was obtained.

The reactivity of the DIBOA-Glc was confirmed in a 16 hour assay with atrazine, which resulted in 48.5% ± 1.2% (SD) atrazine degradation. The tactic described right here provides a number of benefits over present extraction and synthesis strategies, that are extra cumbersome, use hazardous chemical compounds, and yield solely small portions of purified compound. The newly developed methodology will facilitate future analysis characterizing the chemical conduct of DIBOA-Glc and decide its potential as an atrazine mitigation and remediation software.

Human recombinant area antibodies in opposition to a number of sclerosis antigenic peptide CSF114(Glc).

A number of sclerosis (MS) is a power auto-immune illness characterised by a injury to the myelin part of the central nervous system. Self-antigens created by aberrant glycosylation have been described to be a key part within the formation of auto-antibodies.  We reasoned that antibodies raised in opposition to this probe may have been related for MS.

Anti-Myc magnetic beads
B26301	Bimake	1 mL	EUR 579.6
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification.

Anti-Myc magnetic beads
B26302	Bimake	5 mL	EUR 1742.4
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification.

Anti-HA Magnetic Beads
HY-K0201	MedChemExpress	1 mL	EUR 334.8

Protein A Magnetic Beads
HY-K0203	MedChemExpress	1 mL	EUR 148.8

Protein G Magnetic Beads
HY-K0204	MedChemExpress	5 mL	EUR 445.2

Anti-Flag Magnetic Beads
HY-K0207	MedChemExpress	1 mL	EUR 570

Protein A Magnetic Beads
6507-1	Biovision	each	EUR 314.4

Protein G Magnetic Beads
6517-1	Biovision	each	EUR 314.4

Protein L Magnetic Beads
6537-1	Biovision	each	EUR 352.8

Protein A/G Magnetic Beads
HY-K0202	MedChemExpress	1 mL	EUR 157.2

Anti-c-Myc Magnetic Beads
HY-K0206	MedChemExpress	5 mL	EUR 1368

Protein A/G Magnetic Beads
6527-1	Biovision	each	EUR 352.8

Size Selection DNA Beads
20-abx298001	Abbexa	EUR 260.40 EUR 477.60 EUR 1663.20	1 ml 5 ml 60 ml

VAHTS DNA Clean Beads
N411-01	Vazyme	5 ml	EUR 259.2

VAHTS DNA Clean Beads
N411-02	Vazyme	60 ml	EUR 634.8

VAHTS DNA Clean Beads
N411-03	Vazyme	450 ml	EUR 3055.2

Protein A/G/L Magnetic Beads
6547-1	Biovision	each	EUR 405.6

Protein A/G Magnetic Beads for IP
B23201	Bimake	1 ml	EUR 158.4
Description: Protein A/G Magnetic Beads for immunoprecipitation (IP) are based on a biological nanosurface technology (S-TEC). Protein A/G coats the surface of super paramagnetic microspheres with high coating density up to 9.3 × 10^13 molecules/cm2. Compared to similar immune magnetic beads, our Protein A/G beads display much more antibody binding sites therefore using less magnetic beads per reaction and ultimately achiving greater cost-efficiency. Non-specific binding is reduced to an absolute low eliminating any detectable interference with your IP assays. The large, specific surface area of the beads greatly shortens the adsorption time and achieves complete antibody/antigen adsorption process in 10 minutes and complete total purification and precipitation in just 30 minutes. This product can be used on a wide variety of samples, such as in cell lysates, supernatants collected from cell secretion, serum, ascites, and other immune antigens.

Protein A/G Magnetic Beads for IP
B23202	Bimake	5 ml	EUR 558
Description: Protein A/G Magnetic Beads for immunoprecipitation (IP) are based on a biological nanosurface technology (S-TEC). Protein A/G coats the surface of super paramagnetic microspheres with high coating density up to 9.3 × 10^13 molecules/cm2. Compared to similar immune magnetic beads, our Protein A/G beads display much more antibody binding sites therefore using less magnetic beads per reaction and ultimately achiving greater cost-efficiency. Non-specific binding is reduced to an absolute low eliminating any detectable interference with your IP assays. The large, specific surface area of the beads greatly shortens the adsorption time and achieves complete antibody/antigen adsorption process in 10 minutes and complete total purification and precipitation in just 30 minutes. This product can be used on a wide variety of samples, such as in cell lysates, supernatants collected from cell secretion, serum, ascites, and other immune antigens.

Protein A Beads (1-2mg/ml)
B0001-10	BosterBio	10ml	EUR 486

Protein A Beads (1-2mg/ml)
B0001-25	BosterBio	25ml	EUR 973.2

Protein A Beads (1-2mg/ml)
B0001-5	BosterBio	5ml	EUR 291.6

Protein G Beads (1-2mg/ml)
B0002-10	BosterBio	10ml	EUR 729.6

Protein G Beads (1-2mg/ml)
B0002-25	BosterBio	25ml	EUR 1472.4

Protein G Beads (1-2mg/ml)
B0002-5	BosterBio	5ml	EUR 426

100 BP DNA LADDER, 500UL PER KIT
M-DNA-100BP	CORNING	1/pk	EUR 87.6
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT
M-DNA-1KB	CORNING	1/pk	EUR 84
Description: Bioscience Mol Bio; DNA Ladder

Bottle Centrifuge Pp 450 Ml
3141-0500	Scientific Laboratory Supplies	PK4	EUR 152.76

Magnetic Beads-conjugated Mouse anti DDDDK-Tag mAb
AE037	Abclonal	50 ul	EUR 211.2

Beads-for-Seeds (24 glass beads, each in a 1.5 ml tube)
M-CO-501	MiTeGen	24 glass beads	EUR 71
Description: Beads-for-Seeds (24 glass beads, each in a 1.5 ml tube)

FAB & Beads(Ballotini Beads)
MED1042	Scientific Laboratory Supplies	PK50	EUR 91.2

Goat Anti-Rabbit IgG Beads (1-1.5mg/ml)
B0003-10	BosterBio	10ml	EUR 681.6

Goat Anti-Rabbit IgG Beads (1-1.5mg/ml)
B0003-25	BosterBio	25ml	EUR 1228.8

Goat Anti-Rabbit IgG Beads (1-1.5mg/ml)
B0003-5	BosterBio	5ml	EUR 426

Goat Anti-Mouse IgG Beads (1-1.5mg/ml)
B0004-10	BosterBio	10ml	EUR 644.4

Goat Anti-Mouse IgG Beads (1-1.5mg/ml)
B0004-25	BosterBio	25ml	EUR 1228.8

Goat Anti-Mouse IgG Beads (1-1.5mg/ml)
B0004-5	BosterBio	5ml	EUR 400.8

Rabbit Anti-Human IgG Beads (1-1.5mg/ml)
B0005-10	BosterBio	10ml	EUR 949.2

Rabbit Anti-Human IgG Beads (1-1.5mg/ml)
B0005-25	BosterBio	25ml	EUR 2008.8

Rabbit Anti-Human IgG Beads (1-1.5mg/ml)
B0005-5	BosterBio	5ml	EUR 547.2

Rabbit Anti-Rat IgG Beads (1-1.5mg/ml)
B0006-10	BosterBio	10ml	EUR 949.2

Rabbit Anti-Rat IgG Beads (1-1.5mg/ml)
B0006-25	BosterBio	25ml	EUR 2008.8

Rabbit Anti-Rat IgG Beads (1-1.5mg/ml)
B0006-5	BosterBio	5ml	EUR 547.2

Mouse Anti-Rabbit IgG Beads (1-1.5mg/ml)
B0007-10	BosterBio	10ml	EUR 644.4

Mouse Anti-Rabbit IgG Beads (1-1.5mg/ml)
B0007-25	BosterBio	25ml	EUR 1228.8

Mouse Anti-Rabbit IgG Beads (1-1.5mg/ml)
B0007-5	BosterBio	5ml	EUR 400.8

Mouse Anti-Human IgG Beads (1-1.5mg/ml)
B0008-10	BosterBio	10ml	EUR 949.2

Mouse Anti-Human IgG Beads (1-1.5mg/ml)
B0008-25	BosterBio	25ml	EUR 2008.8

Mouse Anti-Human IgG Beads (1-1.5mg/ml)
B0008-5	BosterBio	5ml	EUR 547.2

Circulating DNA Kit (with Magnetic Stand)
abx098869-50rxns	Abbexa	50 rxns	EUR 510

Circulating DNA Kit (with Magnetic Stand)
abx298026-50rxns	Abbexa	50 rxns	EUR 510

RNA/DNA Purification Kit (Magnetic Bead)
DA0623	Daan Gene	32 test/kit	Ask for price

Cyanine7 tetrazine, 25 mg
450	Lumiprobe	25 mg	EUR 615.6

Blood Genomic DNA Kit (with Magnetic Stand)
abx098867-50rxns	Abbexa	50 rxns	EUR 360

Viral DNA / RNA Kit (with Magnetic Stand)
abx098871-50rxns	Abbexa	50 rxns	EUR 477.6

Viral DNA/RNA Kit (with Magnetic Stand)
abx298029-50rxns	Abbexa	50 rxns	EUR 477.6

Latex Beads
abx291003-1L	Abbexa	1 L	EUR 2798.4

RNA Beads
20-abx298002	Abbexa	EUR 260.40 EUR 477.60 EUR 1663.20	1 ml 5 ml 60 ml

Bulk Beads
D1131-01	Benchmark Scientific	1 PC	EUR 285.76

Bulk Beads
D1131-05	Benchmark Scientific	1 PC	EUR 285.76

Bulk Beads
D1131-10	Benchmark Scientific	1 PC	EUR 492.47

Bulk Beads
D1132-01TP	Benchmark Scientific	1 PC	EUR 492.47

Bulk Beads
D1132-05TP	Benchmark Scientific	1 PC	EUR 492.47

Bulk Beads
D1132-10TP	Benchmark Scientific	1 PC	EUR 492.47

Bulk Beads
D1132-15TP	Benchmark Scientific	1 PC	EUR 492.47

Bulk Beads
D1132-30TP	Benchmark Scientific	1 PC	EUR 492.47

Bulk Beads
D1132-60	Benchmark Scientific	1 PC	EUR 289.93

Bulk Beads
D1133-28	Benchmark Scientific	1 PC	EUR 112.45

Exorose Beads
EXOB-100	ABTBeads	100 ml	EUR 127.2

Exorose Beads
EXOB-25	ABTBeads	25 ml	EUR 69.6

Exorose Beads
EXOB-250	ABTBeads	250 ml	EUR 225.6

Saline & Beads
MED1064	Scientific Laboratory Supplies	PK50	EUR 91.2

T4 DNA Polymerase (5,000 U/ml)
RK20539	Abclonal	25 U	Ask for price

Refill Glass Beads
B1201-BEAD	Benchmark Scientific	1 PC	EUR 141.34

V5 agarose beads
AE029-100ul	Abclonal	100 ul	Ask for price

V5 agarose beads
AE029-200ul	Abclonal	200 ul	EUR 273.6

V5 agarose beads
AE029-20ul	Abclonal	20 ul	Ask for price

V5 agarose beads
AE029-50ul	Abclonal	50 ul	Ask for price

Glass Beads 0.1mm
GB01	Next Advance	1pack	EUR 129.6
Description: Glass beads. 0.1mm. 1 lb. Non-sterile.

Glass Beads 0.5mm
GB05	Next Advance	1pack	EUR 123.6
Description: Glass beads. 0.5mm. 1 lb. Non-sterile.

Glass Beads 1.0mm
GB10	Next Advance	1pack	EUR 123.6
Description: Glass beads. 1.0mm. 1 lb. Non-sterile.

Sodium hydroxide, Beads
SB6789	Bio Basic	500g	EUR 73.21

RanBP1 Agarose Beads
STA-421	Cell Biolabs	400 µg	EUR 686.4
Description: RanBP1 Agarose Beads selectively pull down the active form of Ran. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

Protect beads green
SWA1151	Scientific Laboratory Supplies	PK80	EUR 103.74

Protect Beads White
SWA1155	Scientific Laboratory Supplies	PK80	EUR 103.74

Protect Beads Blue
SWA1158	Scientific Laboratory Supplies	PK80	EUR 103.74

Thrombin Sepharose Beads
7925-1	Biovision	each	EUR 261.6

Thrombin Sepharose Beads
7925-25	Biovision	each	EUR 2114.4

Thrombin Sepharose Beads
7925-5	Biovision	each	EUR 836.4

Plasmin Sepharose Beads
7926-1	Biovision	each	EUR 261.6

Plasmin Sepharose Beads
7926-25	Biovision	each	EUR 2114.4

Plasmin Sepharose Beads
7926-5	Biovision	each	EUR 836.4

Urokinase Sepharose Beads
7927-1	Biovision	each	EUR 261.6

Urokinase Sepharose Beads
7927-25	Biovision	each	EUR 2114.4

Urokinase Sepharose Beads
7927-5	Biovision	each	EUR 836.4

Immobilized Catalase Beads
7931-1	Biovision	each	EUR 183.6

Immobilized Catalase Beads
7931-10	Biovision	each	EUR 705.6

Calmodulin-Sepharose Beads
7934-1	Biovision	each	EUR 183.6

Calmodulin-Sepharose Beads
7934-10	Biovision	each	EUR 574.8

Calmodulin-Sepharose Beads
7934-5	Biovision	each	EUR 405.6

Streptavidin-Sepharose Beads
6565-10	Biovision	each	EUR 836.4

Streptavidin-Sepharose Beads
6565-100	Biovision	each	Ask for price

Streptavidin-Sepharose Beads
6565-2	Biovision	each	EUR 274.8

Streptavidin-Sepharose Beads
6565-5	Biovision	each	EUR 483.6

EZEnrich? Polyubiquitin Beads
6568-300	Biovision	each	EUR 444

Blood Genomic DNA Kit (0.1-20 ml)
abx098074-For200mlBlood	Abbexa	For 200 ml Blood	EUR 427.2

Blood Genomic DNA Kit (0.1-20 ml)
abx098074-For50mlBlood	Abbexa	For 50 ml Blood	EUR 260.4

illustra Ready-To-Go RT-PCR Beads 0.5 ml tubes 100 rxns
27926601	Scientific Laboratory Supplies	EACH	EUR 414.96

illustra Ready-To-Go RT-PCR Beads 0.2 ml tubes 96 rxns
27926701	Scientific Laboratory Supplies	EACH	EUR 386.46

illustra PuReTaq Ready-To-Go PCR Beads 0.5 ml tubes 100 rxns
27955801	Scientific Laboratory Supplies	EACH	EUR 159.6

Cot I human DNA conc. >=1,1 mg / ml
3001	GeneOn	500 µg	EUR 140.4

VAHTS mRNA Capture Beads
N401-01	Vazyme	24 rxn	EUR 171.6

VAHTS mRNA Capture Beads
N401-02	Vazyme	96 rxn	EUR 306

VAHTS RNA Clean Beads
N412-01	Vazyme	5 ml	EUR 286.8

VAHTS RNA Clean Beads
N412-02	Vazyme	40 ml	EUR 495.6

VAHTS RNA Clean Beads
N412-03	Vazyme	450 ml	EUR 4860

Stainless Steel Beads 0.2mm
SSB02	Next Advance	1pack	EUR 229.2
Description: Stainless steel beads. 0.2mm. 1 lb. Non-sterile.

Stainless Steel Beads 0.5mm
SSB05	Next Advance	1pack	EUR 229.2
Description: Stainless steel beads. 0.5mm. 1 lb. Non-sterile.

Stainless Steel Beads 1.6mm
SSB16	Next Advance	1pack	EUR 304.8
Description: Stainless steel beads. 1.6mm. 1 lb. Non-sterile.

Stainless Steel Beads 2.3mm
SSB23	Next Advance	1pack	EUR 260.4
Description: Stainless steel beads. 2.3mm. 1 lb. Non-sterile.

Stainless Steel Beads 3.2mm
SSB32	Next Advance	1pack	EUR 220.8
Description: Stainless steel beads. 3.2mm. 1 lb. Non-sterile.

Stainless Steel Beads 4.8mm
SSB48	Next Advance	1pack	EUR 220.8
Description: Stainless steel beads. 4.8mm. 1 lb. Non-sterile.

Stainless Steel Beads 6.0mm
SSB60	Next Advance	1pack	EUR 223.2
Description: Stainless steel beads. 6.0mm. 1 lb. Non-sterile.

PAK1 PBD Agarose Beads
STA-411	Cell Biolabs	400 ?g	EUR 686.4
Description: PAK1 PBD Agarose Beads selectively pull down the active form of Rac and Cdc42. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

Rhotekin RBD Agarose Beads
STA-412	Cell Biolabs	400 ?g	EUR 686.4
Description: Rhotekin RBD Agarose Beads selectively pull down the active form of Rho. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

RalGDS RBD Agarose Beads
STA-418	Cell Biolabs	400 µg	EUR 686.4
Description: RalGDS RBD Agarose Beads selectively pull down the active form of Rap. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

GGA3 PBD Agarose Beads
STA-419	Cell Biolabs	400 µg	EUR 686.4
Description: GGA3 PBD Agarose Beads selectively pull down the active form of Arf. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

RalBP1 PBD Agarose Beads
STA-420	Cell Biolabs	400 µg	EUR 686.4
Description: RalBP1 RBD Agarose Beads selectively pull down the active form of Ral. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

Zirconium Oxide Beads 0.15mm
ZrOB015	Next Advance	1pack	EUR 189.6
Description: Fused Zirconium Oxide beads . 0.15mm. 1 lb. Non-sterile.

Zirconium Oxide Beads 0.5mm
ZrOB05	Next Advance	1pack	EUR 189.6
Description: Zirconium Oxide beads . 0.5mm. 1 lb. Non-sterile.

Zirconium Oxide Beads 1.0mm
ZrOB10	Next Advance	1pack	EUR 189.6
Description: Zirconium Oxide beads . 1.0mm. 1 lb. Non-sterile.

Zirconium Oxide Beads 2.0mm
ZrOB20	Next Advance	1pack	EUR 189.6
Description: Zirconium Oxide beads . 2.0mm. 1 lb. Non-sterile.

Zirconium Oxide Beads 2.5mm
ZrOB25	Next Advance	1pack	EUR 189.6
Description: Zirconium Oxide beads . 2.5mm. 1 lb. Non-sterile.

Zirconium Silicate Beads 0.5mm
ZSB05	Next Advance	1pack	EUR 146.4
Description: Zirconium Silicate beads . 0.5mm. 1 lb. Non-sterile.

Zirconium Silicate Beads 1.0mm
ZSB10	Next Advance	1pack	EUR 146.4
Description: Zirconium Silicate beads . 1.0mm. 1 lb. Non-sterile.

Rtg Rapd Analysis Beads
27950001	Scientific Laboratory Supplies	EACH	EUR 804.84

Glass Calibration Beads 4mm
SV144	Scientific Laboratory Supplies	500G	EUR 14.71

Protect Beads Mixed Colours
SWA1147	Scientific Laboratory Supplies	PK80	EUR 103.74

Calibration Beads for MoFlo
B28479	Spherotech	each	EUR 346.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Magnetic Stirrer
abx725038-1Unit	Abbexa	1 Unit	EUR 518.4

Magnetic Stand
abx799001-1Unit	Abbexa	1 Unit	EUR 309.6

Magnetic Separator
B23803	Bimake	2 mL/200 uL/15 mL	EUR 291.6
Description: This Magnetic Separator is a proprietary machine, supportinga the magnetic beads series of products. A core tenent is the use of a superior magnetic, to ensure that magnetic separation step can be completed in a short time.

Magnetic Separator
MagSep1-1	ABTBeads	1/pk	EUR 132

Magnetic Stirrer
H3760-SE	Benchmark Scientific	1 PC	EUR 121.85

Magnetic Stirrer
H4000-S-E	Benchmark Scientific	1 PC	EUR 97.22

Magnetic Stand
HY-K0200	MedChemExpress	200 μL-2 mL-15 mL	EUR 456

RNase-Free Calf Thymus DNA, 1 mg/mL (5x1mL)
9-31065	Biotium	EUR 206.40 EUR 566.40	1tube 5tubes
Description: Minimum order quantity: 1 unit of 5tubes

cfPure® Cell Free DNA Extraction Kit, 100 ml
K5011610	Biochain	1 kit	EUR 537.6

cfPure® Cell Free DNA Extraction Kit, 250 ml
K5011625	Biochain	1 kit	EUR 897.6

Her2 / ErbB2 Recombinant Protein
11-450	ProSci	0.1 mg	EUR 651.3
Description: Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2,HER-2 /neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation .

CSF3 Recombinant Protein
90-450	ProSci	10 ug	EUR 437.1
Description: G-CSF is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNF-alpha and IFN-gamma. Other cell types including fibroblasts, endothelial cells, astrocytes and bone marrow stromal cells can also secrete G-CSF after LPS, IL-1 or TNF-alpha activation. In addition, various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively. G-CSF stimulates growth, differentiation and functions of cells from the neutrophil lineage in vitro. Consistent with its in vitro functions, G-CSF has been found to play important roles in defense against infection, in inflammation and repair and in the maintenance of steady state hematopoiesis. Recombinant human G-CSF has been approved for the amelioration of chemotherapy induced neutropenia as well as for severe chronic neutropenia following marrow transplant.

VEGF-D Recombinant Protein
91-450	ProSci	0.05 mg	EUR 651.3
Description: Vascular endothelial growth factor D (VEGF-D) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. It is highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas. VEGF-D is growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. It undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors.

HLADG Recombinant Protein
92-450	ProSci	0.05 mg	EUR 588.3
Description: Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

Filter for Accuris Microplate Reader
MR9600-450	Benchmark Scientific	1 PC	EUR 241.56

GFP-Rac1 Expression Vector Set
STA-450	Cell Biolabs	1 kit	EUR 1939.2
Description: GFP-Rac1 Expression Vector Set contains 3 vectors: Rac wild type, T17N dominant negative mutant, and Q61L constitutively active mutant. Each vector also contains a GFP reporter sequence.

Recombinant (CHO cells) Hepatitis B Surface Antigen adr subtype (HBsAg)
RP-450	Alpha Diagnostics	20 ug	EUR 196.8

Benzo(j)fluoranthene
S-450	Scientific Laboratory Supplies	1ML	EUR 70.68

Paritaprevir(ABT-450)
20-abx184297	Abbexa	EUR 1496.40 EUR 1095.60	10 mg 5 mg

Glass Beads 0.1mm RNase Free
GB01-RNA	Next Advance	1pack	EUR 115.2
Description: Glass beads. 0.1mm. 4mL. RNase free.

Glass Beads 0.5mm RNase Free
GB05-RNA	Next Advance	1pack	EUR 115.2
Description: Glass beads. 0.5mm. 4mL. RNase free.

Stainless Steel UFO Beads 3.5mm
SSUFO35	Next Advance	1pack	EUR 229.2
Description: Stainless steel UFO beads. 3.5mm. 50mL. Non-sterile.

Stainless Steel UFO Beads 5.6mm
SSUFO56	Next Advance	1pack	EUR 225.6
Description: Stainless steel UFO beads. 5.6mm. 50mL. Non-sterile.

Raf-1 RBD Agarose Beads
STA-410	Cell Biolabs	400 ?g	EUR 686.4
Description: Raf-1 RBD Agarose Beads selectively pull down the active form of Ras. Beads are colored to allow for a visual check. These are the same beads supplied with our Ras Activation Assays. 400 µg.

Flexi-Block + Beads Double Width
BLO2162	Scientific Laboratory Supplies	EACH	EUR 283.86

Flexi-Block + Beads Triple Width
BLO2163	Scientific Laboratory Supplies	EACH	EUR 428.64

500GM Glass beads 2mm 500gm
GS/2	Scientific Laboratory Supplies	500G	EUR 15.28

We subsequently screened a human Area Antibody library in opposition to CSF114(Glc) utilizing magnetic separation as a panning methodology. We obtained and described a number of clones, and the one with the very best indicators was produced as a 6×His-tagged protein to correctly examine the binding properties as a soluble antibody.