The glycan role in the glycopeptide immunogenicity revealed by atomistic simulations and spectroscopic experiments on the multiple sclerosis biomarker CSF114(Glc).

The glycan role in the glycopeptide immunogenicity revealed by atomistic simulations and spectroscopic experiments on the multiple sclerosis biomarker CSF114(Glc).

Glycoproteins are sometimes acknowledged as not-self molecules by antibodies triggering the onset of extreme autoimmune illnesses resembling A number of Sclerosis (MS). Thus, the event of antigen-mimicking biomarkers represents a sexy technique for an early analysis of the illness. An instance is the artificial glycopeptide CSF114(Glc), which was designed and examined as MS biomarker and whose scientific utility was restricted by its diminished capability to detect autoantibodies in MS sufferers. Within the try to enhance the efficacy of CSF114(Glc), we’ve characterised all of the occasions resulting in the ultimate binding of the biomarker to the autoantibody utilizing atomistic simulations, ESR and NMR experiments. The glycosydic moiety performs a major function in the entire course of.

Particularly, in an setting mimicking that used within the scientific checks the glycopeptide assumes a α-helix construction that’s useful for the interplay with the antibody. On this conformation CSF114(Glc) binds the monoclonal antibody mAb8-18C5 equally to the myelin oligodendrocyte glycoprotein MOG, which is a identified MS auto-antigen, thus explaining its diagnostic exercise. Our examine provides new molecular bases to design more practical biomarkers and offers a most legitimate protocol to analyze different methods the place the setting impact is determinant for the organic exercise.

The current examine was carried out to look at the dissipation sample of triazophos on capsicum and danger evaluation of its residues on human beings and to recommend a ready interval for the protection of customers. Following two functions of triazophos (Truzo 40 EC) at 500 and 1000 g a.i. ha(-1), the typical preliminary deposits had been discovered to be 3.61 and 6.26 mg kg(-1), respectively. These residues dissipated beneath the restrict of quantification (LOQ) of 0.05 mg kg(-1) in 10 and 15 days on the beneficial and double the beneficial dosages, respectively. The calculated values of half-life had been 2.31 and a couple of.

14 days at beneficial and double the beneficial dosages, respectively. Theoretical most residue contribution (TMRC) values had been discovered to be 28.eight and 41.6 μg individual(-1) day(-1) at 500 and 1000 g a.i. ha(-1), respectively, and located to be beneath the utmost permissible consumption on capsicum fruit on the seventh day. Subsequently, a ready interval of seven days is recommended for consumption of capsicum sprayed with triazophos on the beneficial dosages.

Preliminary examine on utility of urine amino acids profiling for monitoring of renal tubular damage utilizing GLC-MS.

The early analysis of the nephrotoxic impact of xenobiotics and medicines remains to be an unsolved drawback. Current research recommend a correlation between the nephrotoxic exercise of xenobiotics and elevated focus of amino acids in urine. The introduced examine was targeted on the applying of GLC-MS methodology for amino acids profiling in human urine as a noninvasive methodology for monitoring of kidney situation and tubular damage degree.
The analytic methodology relies on the conversion of the amino acids current within the pattern to tert-butyldimethylsilyl (TBDMS) derivatives and their evaluation by gas-liquid chromatography-mass spectrometry (GLC-MS). The process of urine pattern preparation for chromatographic evaluation was optimized. CSF114(Glc) is an artificial glucopeptide detecting in vitro MS-specific auto-antibodies, and it’s actively utilized in diagnostics and analysis to observe and quantify MS-associated Ig ranges.
The presence of 12 amino acids in a lot of the examined wholesome human urine samples was detected. The numerous variations within the ranges of specific amino acids between sufferers with tubular damage and wholesome controls had been discovered, particularly for lysine, valine, serine, alanine and leucine. We discovered that this strategy based mostly on GLC-MS detection can be utilized in nephrotoxicity research for urine amino acids monitoring in publicity to xenobiotics and medicines.
The glycan role in the glycopeptide immunogenicity revealed by atomistic simulations and spectroscopic experiments on the multiple sclerosis biomarker CSF114(Glc).

A easy methodology for isolation and purification of DIBOA-Glc from Tripsacum dactyloides.

Naturally occurring benzoxazinones (Bx) are a extremely reactive class of compounds which have obtained specific consideration prior to now a number of many years. Lately, we recognized 2-β-D-glucopyranosyloxy-4-hydroxy-1,4-benzoxazin-3-one (DIBOA-Glc) because the compound current within the roots of Japanese gamagrass {Tripsacum dactyloides (L.)} accountable for atrazine degradation. Nonetheless, characterization of the DIBOA-Glc/atrazine degradation response has been restricted on account of difficulties achieve ample portions of purified DIBOA-Glc.

The target of the examine was to develop a easy purification and isolation methodology for acquiring bulk portions of extremely purified DIBOA-Glc. T. dactyloides roots had been extracted with 90% aqueous methanol, and the crude extract was fractionated utilizing an HPLC geared up with a C8 semi-prep column and fraction collector. UHPLC-DAD-MS/MS was used to verify the identification of DIBOA-Glc within the fractions collected. Evaluation by 13C and 1H NMR and DAD indicated that 542 mg of DIBOA-Glc with a purity of>> 99% was obtained.

The reactivity of the DIBOA-Glc was confirmed in a 16 hour assay with atrazine, which resulted in 48.5% ± 1.2% (SD) atrazine degradation. The tactic described right here provides a number of benefits over present extraction and synthesis strategies, that are extra cumbersome, use hazardous chemical compounds, and yield solely small portions of purified compound. The newly developed methodology will facilitate future analysis characterizing the chemical conduct of DIBOA-Glc and decide its potential as an atrazine mitigation and remediation software.

Human recombinant area antibodies in opposition to a number of sclerosis antigenic peptide CSF114(Glc).

A number of sclerosis (MS) is a power auto-immune illness characterised by a injury to the myelin part of the central nervous system. Self-antigens created by aberrant glycosylation have been described to be a key part within the formation of auto-antibodies.  We reasoned that antibodies raised in opposition to this probe may have been related for MS.

Magnetic Beads for DNA Purification

M1502-5 5 ml
EUR 277

FFPE Tissue DNA Extraction Kit - Magnetic Beads

K5011450 1 kit
EUR 256

Streptavidin Magnetic Beads

HY-K0208 5 mL
EUR 538

Control Magnetic Beads

M1302-1
EUR 98

Protein A Magnetic Beads

6507-1
EUR 262

Protein G Magnetic Beads

6517-1
EUR 262

Protein L Magnetic Beads

6537-1
EUR 294

Anti-Flag magnetic beads

B26101 1 mL
EUR 483
Description: Anti-Flag magnetic beads is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody. It is recommended to use for co-immunoprecipitation and protein purification.

Anti-Flag magnetic beads

B26102 5 mL
EUR 1452
Description: Anti-Flag magnetic beads is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody. It is recommended to use for co-immunoprecipitation and protein purification.

Anti-HA magnetic beads

B26201 1 mL
EUR 483
Description: Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification.

Anti-HA magnetic beads

B26202 5 mL
EUR 1452
Description: Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification.

Anti-Myc magnetic beads

B26301 1 mL
EUR 483
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification.

Anti-Myc magnetic beads

B26302 5 mL
EUR 1452
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification.

Anti-HA Magnetic Beads

HY-K0201 1 mL
EUR 279

Protein A Magnetic Beads

HY-K0203 1 mL
EUR 124

Protein G Magnetic Beads

HY-K0204 5 mL
EUR 371

Anti-Flag Magnetic Beads

HY-K0207 1 mL
EUR 475

Protein A/G Magnetic Beads

6527-1
EUR 294

Protein A/G Magnetic Beads

HY-K0202 1 mL
EUR 131

Anti-c-Myc Magnetic Beads

HY-K0206 5 mL
EUR 1140

Size Selection DNA Beads

20-abx298001
  • EUR 217.00
  • EUR 398.00
  • EUR 1386.00
  • 1 ml
  • 5 ml
  • 60 ml
  • Shipped within 5-10 working days.

VAHTS DNA Clean Beads

N411-01 5 ml
EUR 216

VAHTS DNA Clean Beads

N411-02 60 ml
EUR 529

VAHTS DNA Clean Beads

N411-03 450 ml
EUR 2546

Protein A/G/L Magnetic Beads

6547-1
EUR 338

Protein A Beads (1-2mg/ml)

B0001-10 10ml
EUR 405

Protein A Beads (1-2mg/ml)

B0001-25 25ml
EUR 811

Protein A Beads (1-2mg/ml)

B0001-5 5ml
EUR 243

Protein G Beads (1-2mg/ml)

B0002-10 10ml
EUR 608

Protein G Beads (1-2mg/ml)

B0002-25 25ml
EUR 1227

Protein G Beads (1-2mg/ml)

B0002-5 5ml
EUR 355

Protein A/G Magnetic Beads for IP

B23201 1 ml
EUR 132
Description: Protein A/G Magnetic Beads for immunoprecipitation (IP) are based on a biological nanosurface technology (S-TEC). Protein A/G coats the surface of super paramagnetic microspheres with high coating density up to 9.3 × 10^13 molecules/cm2. Compared to similar immune magnetic beads, our Protein A/G beads display much more antibody binding sites therefore using less magnetic beads per reaction and ultimately achiving greater cost-efficiency. Non-specific binding is reduced to an absolute low eliminating any detectable interference with your IP assays. The large, specific surface area of the beads greatly shortens the adsorption time and achieves complete antibody/antigen adsorption process in 10 minutes and complete total purification and precipitation in just 30 minutes. This product can be used on a wide variety of samples, such as in cell lysates, supernatants collected from cell secretion, serum, ascites, and other immune antigens.

Protein A/G Magnetic Beads for IP

B23202 5 ml
EUR 465
Description: Protein A/G Magnetic Beads for immunoprecipitation (IP) are based on a biological nanosurface technology (S-TEC). Protein A/G coats the surface of super paramagnetic microspheres with high coating density up to 9.3 × 10^13 molecules/cm2. Compared to similar immune magnetic beads, our Protein A/G beads display much more antibody binding sites therefore using less magnetic beads per reaction and ultimately achiving greater cost-efficiency. Non-specific binding is reduced to an absolute low eliminating any detectable interference with your IP assays. The large, specific surface area of the beads greatly shortens the adsorption time and achieves complete antibody/antigen adsorption process in 10 minutes and complete total purification and precipitation in just 30 minutes. This product can be used on a wide variety of samples, such as in cell lysates, supernatants collected from cell secretion, serum, ascites, and other immune antigens.

Magnetic Beads-conjugated Mouse anti DDDDK-Tag mAb

AE037 50 ul
EUR 176

100 BP DNA LADDER, 500UL PER KIT

M-DNA-100BP 1/pk
EUR 73
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT

M-DNA-1KB 1/pk
EUR 70
Description: Bioscience Mol Bio; DNA Ladder

Goat Anti-Rabbit IgG Beads (1-1.5mg/ml)

B0003-10 10ml
EUR 568

Goat Anti-Rabbit IgG Beads (1-1.5mg/ml)

B0003-25 25ml
EUR 1024

Goat Anti-Rabbit IgG Beads (1-1.5mg/ml)

B0003-5 5ml
EUR 355

Goat Anti-Mouse IgG Beads (1-1.5mg/ml)

B0004-10 10ml
EUR 537

Goat Anti-Mouse IgG Beads (1-1.5mg/ml)

B0004-25 25ml
EUR 1024

Goat Anti-Mouse IgG Beads (1-1.5mg/ml)

B0004-5 5ml
EUR 334

Rabbit Anti-Human IgG Beads (1-1.5mg/ml)

B0005-10 10ml
EUR 791

Rabbit Anti-Human IgG Beads (1-1.5mg/ml)

B0005-25 25ml
EUR 1674

Rabbit Anti-Human IgG Beads (1-1.5mg/ml)

B0005-5 5ml
EUR 456

Rabbit Anti-Rat IgG Beads (1-1.5mg/ml)

B0006-10 10ml
EUR 791

Rabbit Anti-Rat IgG Beads (1-1.5mg/ml)

B0006-25 25ml
EUR 1674

Rabbit Anti-Rat IgG Beads (1-1.5mg/ml)

B0006-5 5ml
EUR 456

Mouse Anti-Rabbit IgG Beads (1-1.5mg/ml)

B0007-10 10ml
EUR 537

Mouse Anti-Rabbit IgG Beads (1-1.5mg/ml)

B0007-25 25ml
EUR 1024

Mouse Anti-Rabbit IgG Beads (1-1.5mg/ml)

B0007-5 5ml
EUR 334

Mouse Anti-Human IgG Beads (1-1.5mg/ml)

B0008-10 10ml
EUR 791

Mouse Anti-Human IgG Beads (1-1.5mg/ml)

B0008-25 25ml
EUR 1674

Mouse Anti-Human IgG Beads (1-1.5mg/ml)

B0008-5 5ml
EUR 456

Circulating DNA Kit (with Magnetic Stand)

abx098869-50rxns 50 rxns
EUR 425
  • Shipped within 5-10 working days.

Circulating DNA Kit (with Magnetic Stand)

abx298026-50rxns 50 rxns
EUR 425
  • Shipped within 5-10 working days.

VALI Medium

450 500 ml
EUR 265

Blood Genomic DNA Kit (with Magnetic Stand)

abx098867-50rxns 50 rxns
EUR 300
  • Shipped within 5-10 working days.

Viral DNA / RNA Kit (with Magnetic Stand)

abx098871-50rxns 50 rxns
EUR 398
  • Shipped within 5-10 working days.

Viral DNA/RNA Kit (with Magnetic Stand)

abx298029-50rxns 50 rxns
EUR 398
  • Shipped within 5-10 working days.

Bulk Beads

D1131-01 1 PC
EUR 238.13
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1131-05 1 PC
EUR 238.13
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1131-10 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-01TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-05TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-10TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-15TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-30TP 1 PC
EUR 410.39
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1132-60 1 PC
EUR 241.61
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Bulk Beads

D1133-28 1 PC
EUR 93.71
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Latex Beads

abx291003-1L 1 L
EUR 2332
  • Shipped within 2 months.

RNA Beads

20-abx298002
  • EUR 217.00
  • EUR 398.00
  • EUR 1386.00
  • 1 ml
  • 5 ml
  • 60 ml
  • Shipped within 5-10 working days.

Exorose Beads

EXOB-100 100 ml
EUR 106

Exorose Beads

EXOB-25 25 ml
EUR 58

Exorose Beads

EXOB-250 250 ml
EUR 188

Blood Genomic DNA Kit (0.1-20 ml)

abx098074-For200mlBlood For 200 ml Blood
EUR 356
  • Shipped within 5-10 working days.

Blood Genomic DNA Kit (0.1-20 ml)

abx098074-For50mlBlood For 50 ml Blood
EUR 217
  • Shipped within 5-10 working days.

Paritaprevir(ABT-450)

20-abx184297
  • EUR 1247.00
  • EUR 913.00
  • 10 mg
  • 5 mg
  • Shipped within 1-2 weeks.

Streptavidin-Sepharose Beads

6565-10
EUR 697

Streptavidin-Sepharose Beads

6565-100 Ask for price

Streptavidin-Sepharose Beads

6565-2
EUR 229

Streptavidin-Sepharose Beads

6565-5
EUR 403

EZEnrich? Polyubiquitin Beads

6568-300
EUR 370

Refill Glass Beads

B1201-BEAD 1 PC
EUR 117.78
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Thrombin Sepharose Beads

7925-1
EUR 218

Thrombin Sepharose Beads

7925-25
EUR 1762

Thrombin Sepharose Beads

7925-5
EUR 697

Plasmin Sepharose Beads

7926-1
EUR 218

Plasmin Sepharose Beads

7926-25
EUR 1762

Plasmin Sepharose Beads

7926-5
EUR 697

Urokinase Sepharose Beads

7927-1
EUR 218

Urokinase Sepharose Beads

7927-25
EUR 1762

Urokinase Sepharose Beads

7927-5
EUR 697

Immobilized Catalase Beads

7931-1
EUR 153

Immobilized Catalase Beads

7931-10
EUR 588

Calmodulin-Sepharose Beads

7934-1
EUR 153

Calmodulin-Sepharose Beads

7934-10
EUR 479

Calmodulin-Sepharose Beads

7934-5
EUR 338

V5 agarose beads

AE029-100ul 100 ul Ask for price

V5 agarose beads

AE029-200ul 200 ul
EUR 228

V5 agarose beads

AE029-20ul 20 ul Ask for price

V5 agarose beads

AE029-50ul 50 ul Ask for price

Glass Beads 0.1mm

GB01 1pack
EUR 108
Description: Glass beads. 0.1mm. 1 lb. Non-sterile.

Glass Beads 0.5mm

GB05 1pack
EUR 103
Description: Glass beads. 0.5mm. 1 lb. Non-sterile.

Glass Beads 1.0mm

GB10 1pack
EUR 103
Description: Glass beads. 1.0mm. 1 lb. Non-sterile.

RanBP1 Agarose Beads

STA-421 400 µg
EUR 572
Description: RanBP1 Agarose Beads selectively pull down the active form of Ran. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

Sodium hydroxide, Beads

SB6789 500g
EUR 61.01
  • Product category: Biochemicals/Adsorbents/Drying Agents/Adsorbents

Cot I human DNA conc. >=1,1 mg / ml

3001 500 µg
EUR 117

BrightGreen miRNA qPCR MasterMix-Low ROX

MasterMix-mL 4 x 1.25 ml for 500 reactions
EUR 151

Rat Monoclonal Anti-Mouse CD4 Pur. Low Endotoxin (Clone YTS 191.1) (rat IgG2b)

MCD004-ML 100 ug
EUR 408

Rat Monoclonal Anti-Mouse CD25 , Pur. Low Endotoxin (Clone PC61.5.3) (rat IgG1)

MCD025-ML 100 ug
EUR 408

AKT1 (Ab-450) Antibody

21502-100ul 100ul
EUR 252

AKT1 (Ab-450) Antibody

21502-50ul 50ul
EUR 187

iFluor™ 450 maleimide

1057 1 mg
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

AKT1 (Ab-450) Antibody

CSB-PA969941-
EUR 335
  • Form: liquid
  • Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibo
  • Show more
Description: A polyclonal antibody against AKT1 (Ab-450). Recognizes AKT1 (Ab-450) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

AKT1 (Ab-450) Antibody

CSB-PA969941-100ul 100ul
EUR 316
  • Form: liquid
  • Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibo
  • Show more
Description: A polyclonal antibody against AKT1 (Ab-450). Recognizes AKT1 (Ab-450) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

anti-AKT1 (Ab-450)

LF-PA20679 100 ul
EUR 334
Description: Rabbit polyclonal to AKT1

Nhe I unit: 450

YRNHE1 1 vial Ask for price

Calibration Beads for MoFlo

B28479
EUR 289
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

VAHTS mRNA Capture Beads

N401-01 24 rxn
EUR 143

VAHTS mRNA Capture Beads

N401-02 96 rxn
EUR 255

VAHTS RNA Clean Beads

N412-01 5 ml
EUR 239

VAHTS RNA Clean Beads

N412-02 40 ml
EUR 413

VAHTS RNA Clean Beads

N412-03 450 ml
EUR 4050

Stainless Steel Beads 0.2mm

SSB02 1pack
EUR 191
Description: Stainless steel beads. 0.2mm. 1 lb. Non-sterile.

Stainless Steel Beads 0.5mm

SSB05 1pack
EUR 191
Description: Stainless steel beads. 0.5mm. 1 lb. Non-sterile.

Stainless Steel Beads 1.6mm

SSB16 1pack
EUR 254
Description: Stainless steel beads. 1.6mm. 1 lb. Non-sterile.

Stainless Steel Beads 2.3mm

SSB23 1pack
EUR 217
Description: Stainless steel beads. 2.3mm. 1 lb. Non-sterile.

Stainless Steel Beads 3.2mm

SSB32 1pack
EUR 184
Description: Stainless steel beads. 3.2mm. 1 lb. Non-sterile.

Stainless Steel Beads 4.8mm

SSB48 1pack
EUR 184
Description: Stainless steel beads. 4.8mm. 1 lb. Non-sterile.

Stainless Steel Beads 6.0mm

SSB60 1pack
EUR 186
Description: Stainless steel beads. 6.0mm. 1 lb. Non-sterile.

PAK1 PBD Agarose Beads

STA-411 400 ?g
EUR 572
Description: PAK1 PBD Agarose Beads selectively pull down the active form of Rac and Cdc42. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

Rhotekin RBD Agarose Beads

STA-412 400 ?g
EUR 572
Description: Rhotekin RBD Agarose Beads selectively pull down the active form of Rho. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

RalGDS RBD Agarose Beads

STA-418 400 µg
EUR 572
Description: RalGDS RBD Agarose Beads selectively pull down the active form of Rap. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

GGA3 PBD Agarose Beads

STA-419 400 µg
EUR 572
Description: GGA3 PBD Agarose Beads selectively pull down the active form of Arf. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

RalBP1 PBD Agarose Beads

STA-420 400 µg
EUR 572
Description: RalBP1 RBD Agarose Beads selectively pull down the active form of Ral. Beads are colored to allow for a visual check. These are the same beads supplied with our Small GTPase Activation Assays. 400 µg.

Zirconium Oxide Beads 0.15mm

ZrOB015 1pack
EUR 158
Description: Fused Zirconium Oxide beads . 0.15mm. 1 lb. Non-sterile.

Zirconium Oxide Beads 0.5mm

ZrOB05 1pack
EUR 158
Description: Zirconium Oxide beads . 0.5mm. 1 lb. Non-sterile.

Zirconium Oxide Beads 1.0mm

ZrOB10 1pack
EUR 158
Description: Zirconium Oxide beads . 1.0mm. 1 lb. Non-sterile.

Zirconium Oxide Beads 2.0mm

ZrOB20 1pack
EUR 158
Description: Zirconium Oxide beads . 2.0mm. 1 lb. Non-sterile.

Zirconium Oxide Beads 2.5mm

ZrOB25 1pack
EUR 158
Description: Zirconium Oxide beads . 2.5mm. 1 lb. Non-sterile.

Zirconium Silicate Beads 0.5mm

ZSB05 1pack
EUR 122
Description: Zirconium Silicate beads . 0.5mm. 1 lb. Non-sterile.

Zirconium Silicate Beads 1.0mm

ZSB10 1pack
EUR 122
Description: Zirconium Silicate beads . 1.0mm. 1 lb. Non-sterile.

Cot I human DNA HC conc. >=9 mg / ml

3005 5 mg Ask for price

RNase-Free Calf Thymus DNA, 1 mg/mL (5x1mL)

9-31065
  • EUR 172.00
  • EUR 472.00
  • 1tube
  • 5tubes
Description: Minimum order quantity: 1 unit of 5tubes

cfPure® Cell Free DNA Extraction Kit, 100 ml

K5011610 1 kit
EUR 448

cfPure® Cell Free DNA Extraction Kit, 250 ml

K5011625 1 kit
EUR 748

Magnetic Separator

B23803 2 mL/200 uL/15 mL
EUR 243
Description: This Magnetic Separator is a proprietary machine, supportinga the magnetic beads series of products. A core tenent is the use of a superior magnetic, to ensure that magnetic separation step can be completed in a short time.

Magnetic Stirrer

abx725038-1Unit 1 Unit
EUR 432
  • Shipped within 10-15 working days.

Magnetic Stand

abx799001-1Unit 1 Unit
EUR 258
  • Shipped within 5-10 working days.

Magnetic Stirrer

H3760-SE 1 PC
EUR 101.54
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Magnetic Stirrer

H4000-S-E 1 PC
EUR 81.02
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Magnetic Stand

HY-K0200 200 μL-2 mL-15 mL
EUR 380

Magnetic Separator

MagSep1-1 1/pk
EUR 110

mFluor™ Violet 450 acid

1140 5 mg
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

mFluor™ Violet 450 SE

1150 1 mg
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

mFluor™ 450-VAD-FMK

13475 25 Tests
EUR 132
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Polyclonal TLR1 Antibody (aa400-450)

APR02824G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TLR1 (aa400-450). This antibody is tested and proven to work in the following applications:

Polyclonal CYP1B1 Antibody (aa400-450)

APG02857G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CYP1B1 (aa400-450). This antibody is tested and proven to work in the following applications:

Polyclonal SNX4 Antibody (aa438-450)

AMM07924G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human SNX4 (aa438-450). This antibody is tested and proven to work in the following applications:

Polyclonal PACSIN2 Antibody (aa400-450)

APR17733G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PACSIN2 (aa400-450). This antibody is tested and proven to work in the following applications:

AKT1 (Ab-450) Conjugated Antibody

C21502 100ul
EUR 397

cfPure® V2 Cell Free DNA Extraction Kit, 100 ml

K5011610-V2 1 kit
EUR 448

cfPure® V2 Cell Free DNA Extraction Kit, 250 ml

K5011625-V2 1 kit
EUR 748

Calibration Beads for MoFlo Astrios

B27034
EUR 289
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Glass Beads 0.1mm RNase Free

GB01-RNA 1pack
EUR 96
Description: Glass beads. 0.1mm. 4mL. RNase free.

We subsequently screened a human Area Antibody library in opposition to CSF114(Glc) utilizing magnetic separation as a panning methodology. We obtained and described a number of clones, and the one with the very best indicators was produced as a 6×His-tagged protein to correctly examine the binding properties as a soluble antibody.

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